C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: major histocompatibility complex, class II, DP beta 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000230763 HLA-DPB1 9606 + CHR_HSCHR6_MHC_MCF_CTG1:33109380-33120645 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000411558 HLA-DPB1-003 33109426-33120645 protein_coding
  ENST00000425130 HLA-DPB1-001 33109380-33120645 protein_coding
  ENST00000445702 HLA-DPB1-008 33113947-33119333 protein_coding
  ENST00000455122 HLA-DPB1-002 33114132-33120645 protein_coding
  ENST00000481615 HLA-DPB1-006 33113846-33117472 processed_transcript
  ENST00000487219 HLA-DPB1-004 33109464-33114692 retained_intron
  ENST00000491374 HLA-DPB1-005 33113846-33118401 processed_transcript
  ENST00000493369 HLA-DPB1-009 33114401-33117350 processed_transcript
  ENST00000494240 HLA-DPB1-007 33113903-33118675 processed_transcript

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0005515 IEA protein binding
GO:0005765 TAS lysosomal membrane
GO:0005768 IEA endosome
GO:0005886 TAS plasma membrane
GO:0006955 IEA immune response
GO:0009986 IMP cell surface
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IEA membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0019886 IMP antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030658 TAS transport vesicle membrane
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0031295 TAS T cell costimulation
GO:0032588 TAS trans-Golgi network membrane
GO:0032729 IMP positive regulation of interferon-gamma production
GO:0042102 IMP positive regulation of T cell proliferation
GO:0042605 IDA peptide antigen binding
GO:0042613 IEA MHC class II protein complex
GO:0050852 TAS T cell receptor signaling pathway
GO:0050870 IMP positive regulation of T cell activation
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

No Homologs available.

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