C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 21, subfamily A, polypeptide 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000231852 CYP21A2 9606 + 6:32038265-32041670 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000418967 CYP21A2-002 32038265-32041670 protein_coding
  ENST00000435122 CYP21A2-001 32038415-32041642 protein_coding
  ENST00000462278 CYP21A2-014 32039214-32039972 retained_intron
  ENST00000464325 CYP21A2-012 32038583-32039756 retained_intron
  ENST00000466779 CYP21A2-010 32038327-32039824 nonsense_mediated_decay
  ENST00000466879 CYP21A2-003 32038751-32039823 retained_intron
  ENST00000469053 CYP21A2-011 32038416-32039640 nonsense_mediated_decay
  ENST00000471671 CYP21A2-013 32038415-32039606 protein_coding
  ENST00000478281 CYP21A2-015 32038382-32039433 protein_coding
  ENST00000479074 CYP21A2-004 32038365-32041642 retained_intron
  ENST00000479730 CYP21A2-006 32038365-32041642 retained_intron
  ENST00000480027 CYP21A2-008 32038370-32039115 retained_intron
  ENST00000483041 CYP21A2-007 32038370-32041186 retained_intron
  ENST00000486063 CYP21A2-005 32038340-32041642 retained_intron
  ENST00000488465 CYP21A2-009 32038415-32039484 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; LiverENST00000418967
Transcript ID Liver
ENST00000418967 6.525±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000424 CIL_000424_0001 CGP 6:32014762-32041670

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004497 IEA monooxygenase activity
GO:0004509 IEA steroid 21-monooxygenase activity
GO:0005496 IEA steroid binding
GO:0005506 IEA iron ion binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006704 TAS glucocorticoid biosynthetic process
GO:0006705 TAS mineralocorticoid biosynthetic process
GO:0006805 TAS xenobiotic metabolic process
GO:0008202 TAS steroid metabolic process
GO:0008395 TAS steroid hydroxylase activity
GO:0016125 TAS sterol metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 IEA heme binding
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037550 cyp21a2 cytochrome P450, family 21, subfamily A, polypeptide 2 protein_coding Danio_rerio
ENSMUSG00000024365 Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 protein_coding Mus_musculus

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