C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: major histocompatibility complex, class I, G
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000235346 HLA-G 9606 + CHR_HSCHR6_MHC_DBB_CTG1:29824187-29828345 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000420559 HLA-G-002 29824187-29828345 protein_coding
  ENST00000423373 HLA-G-001 29825041-29828345 protein_coding
  ENST00000452577 HLA-G-004 29825065-29828345 protein_coding
  ENST00000457132 HLA-G-006 29825065-29828345 protein_coding
  ENST00000469347 HLA-G-005 29825065-29828345 nonsense_mediated_decay
  ENST00000484755 HLA-G-003 29825065-29828345 retained_intron
  ENST00000546634 HLA-G-205 29824199-29828342 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0001916 IEA positive regulation of T cell mediated cytotoxicity
GO:0002474 IEA:TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002480 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0002666 IMP positive regulation of T cell tolerance induction
GO:0002767 IDA immune response-inhibiting cell surface receptor signaling pathway
GO:0005102 IPI receptor binding
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006955 IEA immune response
GO:0006968 TAS cellular defense response
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0030670 TAS phagocytic vesicle membrane
GO:0031901 TAS early endosome membrane
GO:0032735 IDA positive regulation of interleukin-12 production
GO:0042130 IDA negative regulation of T cell proliferation
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042605 IEA peptide antigen binding
GO:0042612 IEA MHC class I protein complex
GO:0042803 NAS protein homodimerization activity
GO:0045591 IMP positive regulation of regulatory T cell differentiation
GO:0050776 TAS regulation of immune response
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane
GO:2001199 IDA negative regulation of dendritic cell differentiation

Homologs

No Homologs available.

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