C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: major histocompatibility complex, class I, A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000235657 HLA-A 9606 + CHR_HSCHR6_MHC_DBB_CTG1:29931219-29935859 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000438861 HLA-A-002 29932205-29935859 protein_coding
  ENST00000453975 HLA-A-003 29932509-29935859 protein_coding
  ENST00000457879 HLA-A-001 29931219-29935859 protein_coding
  ENST00000460542 HLA-A-006 29932514-29935256 retained_intron
  ENST00000468666 HLA-A-004 29932508-29935859 retained_intron
  ENST00000470534 HLA-A-007 29932514-29935256 retained_intron
  ENST00000487534 HLA-A-005 29932512-29935859 retained_intron
  ENST00000547271 HLA-A-214 29932430-29935859 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0001916 IDA:IEA positive regulation of T cell mediated cytotoxicity
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002480 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0002486 IDA antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
GO:0005102 IPI receptor binding
GO:0005515 IEA protein binding
GO:0005783 IDA:ISS endoplasmic reticulum
GO:0005794 IDA:ISS Golgi apparatus
GO:0005797 IDA Golgi medial cisterna
GO:0005886 TAS plasma membrane
GO:0006955 IEA immune response
GO:0009986 IDA:ISS cell surface
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IEA membrane
GO:0016032 TAS:IEA viral process
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0030670 TAS phagocytic vesicle membrane
GO:0030881 IDA:ISS beta-2-microglobulin binding
GO:0031901 TAS early endosome membrane
GO:0032729 IDA positive regulation of interferon-gamma production
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042605 IDA:ISS peptide antigen binding
GO:0042608 IDA T cell receptor binding
GO:0042612 IEA MHC class I protein complex
GO:0044822 IDA poly(A) RNA binding
GO:0046977 IDA TAP binding
GO:0050690 TAS regulation of defense response to virus by virus
GO:0050776 TAS regulation of immune response
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:0070971 IDA endoplasmic reticulum exit site
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane
GO:2000568 IDA positive regulation of memory T cell activation

Homologs

No Homologs available.

Loading