C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: major histocompatibility complex, class II, DO alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000235744 HLA-DOA 9606 - CHR_HSCHR6_MHC_DBB_CTG1:32982126-32987559 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000416763 HLA-DOA-003 32985444-32987526 protein_coding
  ENST00000452598 HLA-DOA-001 32982126-32987559 protein_coding
  ENST00000465500 HLA-DOA-002 32986008-32987529 processed_transcript
  ENST00000468742 HLA-DOA-006 32985392-32986071 processed_transcript
  ENST00000478557 HLA-DOA-004 32984748-32986001 retained_intron
  ENST00000484506 HLA-DOA-005 32984554-32985331 processed_transcript
  ENST00000549881 HLA-DOA-207 32984693-32987507 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002587 IDA negative regulation of antigen processing and presentation of peptide antigen via MHC class II
GO:0005515 IEA protein binding
GO:0005765 TAS lysosomal membrane
GO:0005768 IEA endosome
GO:0005886 TAS plasma membrane
GO:0006955 IEA immune response
GO:0007165 TAS signal transduction
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019882 IEA antigen processing and presentation
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0023026 IDA MHC class II protein complex binding
GO:0032395 TAS MHC class II receptor activity
GO:0042613 IDA:IEA MHC class II protein complex

Homologs

No Homologs available.

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