C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: major histocompatibility complex, class II, DM beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000239329 HLA-DMB 9606 - CHR_HSCHR6_MHC_MANN_CTG1:33088404-33106898 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000413038 HLA-DMB-006 33088404-33092463 protein_coding
  ENST00000415927 HLA-DMB-008 33091139-33106898 protein_coding
  ENST00000421456 HLA-DMB-007 33088404-33091214 protein_coding
  ENST00000428420 HLA-DMB-001 33088404-33094845 protein_coding
  ENST00000452407 HLA-DMB-002 33088404-33094796 protein_coding
  ENST00000462635 HLA-DMB-004 33088404-33090676 retained_intron
  ENST00000472082 HLA-DMB-005 33088404-33090661 retained_intron
  ENST00000487546 HLA-DMB-003 33088404-33094759 retained_intron

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002399 IMP MHC class II protein complex assembly
GO:0002503 IDA peptide antigen assembly with MHC class II protein complex
GO:0002504 IEA antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0005515 IEA protein binding
GO:0005765 TAS lysosomal membrane
GO:0005768 IEA endosome
GO:0006955 IEA immune response
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019882 IEA antigen processing and presentation
GO:0019886 IMP antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0023026 IDA MHC class II protein complex binding
GO:0042102 IMP positive regulation of T cell proliferation
GO:0042613 IEA MHC class II protein complex
GO:2001190 IMP positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Homologs

No Homologs available.

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