C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: UDP glucuronosyltransferase 1 family, polypeptide A8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000241635 UGT1A8 9606 + 2:233760248-233773299 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000305208 UGT1A8-001 233760248-233773299 protein_coding
  ENST00000360418 UGT1A8-201 233760288-233771615 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainHeartKidneyLiverMuscleOvaryENST00000305208ENST00000360418
Transcript ID Adipose Adrenal Brain Heart Kidney Liver Muscle Ovary
ENST00000305208 0.087±0.00 N/A 0.027±0.00 N/A 30.476±0.00 233.207±0.00 0.379±0.00 0.107±0.00
ENST00000360418 0.054±0.00 0.112±0.00 0.085±0.00 0.041±0.00 N/A N/A 0.003±0.00 0.038±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007HK CIL_0007HK_0001 CGP 2:233475520-233773310
CIL_0004L1 CIL_0004L1_0008 CGP 2:233617645-233773310
CIL_0004L1 CIL_0004L1_0009 CGP 2:233636454-233773305
CIL_0004L1 CIL_0004L1_0007 CGP 2:233671853-233773300
CIL_0004L1 CIL_0004L1_000B CGP 2:233681938-233773300
CIL_0004L1 CIL_0004L1_0005 CGP 2:233691607-233773300
CIL_0004L1 CIL_0004L1_0006 CGP 2:233712992-233773299
CIL_0004L1 CIL_0004L1_000C CGP 2:233718778-233773299
CIL_0004L1 CIL_0004L1_000A CGP 2:233729108-233773299
CIL_0001B0 CIL_0001B0_0001 CGP 2:233760248-233833423

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001889 IEA liver development
GO:0001972 IDA retinoic acid binding
GO:0004857 IDA enzyme inhibitor activity
GO:0005496 IDA steroid binding
GO:0005783 IDA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005887 IEA integral component of plasma membrane
GO:0005975 IEA carbohydrate metabolic process
GO:0006778 TAS porphyrin-containing compound metabolic process
GO:0006789 TAS bilirubin conjugation
GO:0006805 TAS xenobiotic metabolic process
GO:0006953 IEA acute-phase response
GO:0007584 IEA response to nutrient
GO:0007586 NAS digestion
GO:0008152 IEA metabolic process
GO:0008202 IC steroid metabolic process
GO:0008210 TAS estrogen metabolic process
GO:0010033 IEA response to organic substance
GO:0014070 IEA response to organic cyclic compound
GO:0015020 IDA glucuronosyltransferase activity
GO:0016758 IEA transferase activity, transferring hexosyl groups
GO:0017144 IC drug metabolic process
GO:0019899 IDA enzyme binding
GO:0030246 IEA carbohydrate binding
GO:0030259 IEA lipid glycosylation
GO:0031100 IEA organ regeneration
GO:0032496 IEA response to lipopolysaccharide
GO:0032870 IEA cellular response to hormone stimulus
GO:0042167 TAS heme catabolic process
GO:0042493 IEA response to drug
GO:0042573 IC retinoic acid metabolic process
GO:0042594 IEA response to starvation
GO:0042803 IDA protein homodimerization activity
GO:0043086 IDA negative regulation of catalytic activity
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0045471 IEA response to ethanol
GO:0045939 IC negative regulation of steroid metabolic process
GO:0046483 IC heterocycle metabolic process
GO:0046982 IDA protein heterodimerization activity
GO:0048545 IEA response to steroid hormone
GO:0051384 IEA response to glucocorticoid
GO:0051552 IDA flavone metabolic process
GO:0052695 IDA cellular glucuronidation
GO:0052696 IDA flavonoid glucuronidation
GO:0052697 IDA xenobiotic glucuronidation
GO:0070069 IEA cytochrome complex
GO:0070980 IEA biphenyl catabolic process
GO:0071361 IEA cellular response to ethanol
GO:0071385 IEA cellular response to glucocorticoid stimulus
GO:2001030 IDA negative regulation of cellular glucuronidation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006220 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7 protein_coding Danio_rerio
ENSDARG00000089507 ugt1b5 UDP glucuronosyltransferase 1 family, polypeptide B5 protein_coding Danio_rerio
ENSDARG00000097024 ugt1b4 UDP glucuronosyltransferase 1 family, polypeptide B4 protein_coding Danio_rerio
ENSDARG00000097231 ugt1b2 UDP glucuronosyltransferase 1 family, polypeptide B2 protein_coding Danio_rerio
ENSDARG00000097491 ugt1b1 UDP glucuronosyltransferase 1 family, polypeptide B1 protein_coding Danio_rerio
ENSDARG00000097979 ugt1b3 UDP glucuronosyltransferase 1 family, polypeptide B3 protein_coding Danio_rerio
ENSMUSG00000089960 Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 protein_coding Mus_musculus

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