C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: major histocompatibility complex, class II, DM beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000241674 HLA-DMB 9606 - CHR_HSCHR6_MHC_QBL_CTG1:32863344-32881839 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000383231 HLA-DMB-001 32863344-32869784 protein_coding
  ENST00000415090 HLA-DMB-008 32866079-32881839 protein_coding
  ENST00000428864 HLA-DMB-002 32863344-32869735 protein_coding
  ENST00000430115 HLA-DMB-007 32863344-32866154 protein_coding
  ENST00000438310 HLA-DMB-006 32863344-32867403 protein_coding
  ENST00000463532 HLA-DMB-003 32863344-32869698 retained_intron
  ENST00000473335 HLA-DMB-004 32863344-32865616 retained_intron
  ENST00000475801 HLA-DMB-005 32863344-32865601 retained_intron

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002399 IMP MHC class II protein complex assembly
GO:0002503 IDA peptide antigen assembly with MHC class II protein complex
GO:0002504 IEA antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0005515 IEA protein binding
GO:0005765 TAS lysosomal membrane
GO:0005768 IEA endosome
GO:0006955 IEA immune response
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019882 IEA antigen processing and presentation
GO:0019886 IMP antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0023026 IDA MHC class II protein complex binding
GO:0042102 IMP positive regulation of T cell proliferation
GO:0042613 IDA:IEA MHC class II protein complex
GO:2001190 IMP positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Homologs

No Homologs available.

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