C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) subunit, alpha type, 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000256646 PSMA2 9606 - 7:42909273-42932174 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000433579 PSMA2-002 42910739-42932171 nonsense_mediated_decay
  ENST00000442788 PSMA2-001 42909273-42932174 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000442788
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000442788 4.754±0.00 7.338±0.00 0.721±0.00 4.928±2.92 5.329±2.96 4.652±1.50 3.903±1.98 5.276±2.98 1.588±0.00 3.553±0.81 0.999±0.00 6.657±2.81 5.054±0.44 7.619±4.18

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0000932 ISS cytoplasmic mRNA processing body
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0004175 IEA endopeptidase activity
GO:0004298 IEA threonine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0005839 ISS:IEA proteasome core complex
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0009615 IEP response to virus
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0019773 IEA proteasome core complex, alpha-subunit complex
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035679 si:rp71-45k5.4 si:rp71-45k5.4 protein_coding Danio_rerio
ENSDARG00000040121 psma2 proteasome (prosome, macropain) subunit, alpha type, 2 protein_coding Danio_rerio
ENSMUSG00000015671 Psma2 proteasome (prosome, macropain) subunit, alpha type 2 protein_coding Mus_musculus

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