C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SPECC1L-ADORA2A readthrough (NMD candidate)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000258555 SPECC1L-ADORA2A 9606 + 22:24270898-24442356 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358654 SPECC1L-ADORA2A-001 24270898-24442356 nonsense_mediated_decay
  ENST00000610595 SPECC1L-ADORA2A-201 24432119-24442356 protein_coding
  ENST00000611543 SPECC1L-ADORA2A-202 24423597-24442356 protein_coding
  ENST00000618076 SPECC1L-ADORA2A-203 24432119-24442356 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LungENST00000611543
Transcript ID Lung
ENST00000611543 10.699±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006Z1 CIL_0006Z1_0002 CGP 22:24270817-24442356

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001609 IDA G-protein coupled adenosine receptor activity
GO:0001973 IEA adenosine receptor signaling pathway
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0005887 IMP integral component of plasma membrane
GO:0006171 TAS cAMP biosynthetic process
GO:0006909 TAS phagocytosis
GO:0006915 TAS apoptotic process
GO:0006954 TAS inflammatory response
GO:0006968 TAS cellular defense response
GO:0007169 TAS transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007188 TAS adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007190 TAS activation of adenylate cyclase activity
GO:0007267 TAS cell-cell signaling
GO:0007417 TAS central nervous system development
GO:0007596 TAS blood coagulation
GO:0007600 TAS sensory perception
GO:0008015 TAS blood circulation
GO:0010579 IDA positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0016020 TAS membrane
GO:0016021 IEA integral component of membrane
GO:0019899 IPI enzyme binding
GO:0042802 IPI identical protein binding
GO:0046983 IEA protein dimerization activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033706 adora2aa adenosine A2a receptor a protein_coding Danio_rerio
ENSMUSG00000020178 Adora2a adenosine A2a receptor protein_coding Mus_musculus

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