C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoinositide-3-kinase, regulatory subunit 2 (beta)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000268173 PIK3R2 9606 + 19:18153158-18178117 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000593731 PIK3R2-001 18153158-18178117 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainENST00000593731
Transcript ID Brain
ENST00000593731 0.800±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004E1 CIL_0004E1_0002 CGP 19:18097793-18170540
CIL_0004DQ CIL_0004DQ_0002 CGP 19:18153158-18178117

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005829 TAS cytosol
GO:0005942 IEA phosphatidylinositol 3-kinase complex
GO:0006644 TAS phospholipid metabolic process
GO:0006661 TAS phosphatidylinositol biosynthetic process
GO:0007165 IEA signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007596 TAS blood coagulation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0016303 ISS 1-phosphatidylinositol-3-kinase activity
GO:0030971 IPI receptor tyrosine kinase binding
GO:0035014 IEA phosphatidylinositol 3-kinase regulator activity
GO:0036092 ISS phosphatidylinositol-3-phosphate biosynthetic process
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043551 IEA regulation of phosphatidylinositol 3-kinase activity
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0050852 TAS T cell receptor signaling pathway
GO:0050900 TAS leukocyte migration
GO:0051056 TAS regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018060 pik3r2 phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 protein_coding Danio_rerio
ENSMUSG00000031834 Pik3r2 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) protein_coding Mus_musculus

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