C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ORAI calcium release-activated calcium modulator 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000276045 ORAI1 9606 + 12:121626550-121642677 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000611718 ORAI1-002 121626816-121641533 protein_coding
  ENST00000616379 ORAI1-201 121626550-121642040 protein_coding
  ENST00000617316 ORAI1-001 121626550-121642677 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000611718ENST00000616379ENST00000617316
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000611718 N/A N/A N/A N/A 0.563±0.00 0.952±0.00 N/A N/A N/A 1.181±0.00 N/A 1.183±0.00 N/A 1.898±0.00
ENST00000616379 8.399±0.00 14.858±0.00 N/A 0.943±0.76 6.697±0.00 4.963±4.88 1.746±1.72 7.174±0.00 3.566±3.07 11.110±10.55 8.007±5.84 9.654±6.71 15.545±7.69 6.985±4.50
ENST00000617316 1.501±0.00 5.895±0.00 0.034±0.00 1.189±0.00 1.712±1.31 N/A 0.304±0.23 1.051±0.40 0.771±0.00 1.198±0.96 N/A 1.474±0.00 0.908±0.35 0.857±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007G5 CIL_0007G5_0003 CGP 12:121429097-121642677
CIL_0007G6 CIL_0007G6_0002 CGP 12:121626550-121672631

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002115 IEA store-operated calcium entry
GO:0002376 IEA immune system process
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005887 IDA integral component of plasma membrane
GO:0007596 TAS blood coagulation
GO:0015279 IDA store-operated calcium channel activity
GO:0016020 IDA membrane
GO:0042802 IPI identical protein binding
GO:0043234 IEA protein complex
GO:0051924 IMP regulation of calcium ion transport
GO:0051928 IDA positive regulation of calcium ion transport
GO:0070588 IEA calcium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004154 orai1b ORAI calcium release-activated calcium modulator 1b protein_coding Danio_rerio
ENSDARG00000011515 ORAI1 (2 of 2) ORAI calcium release-activated calcium modulator 1 protein_coding Danio_rerio
ENSMUSG00000049686 Orai1 ORAI calcium release-activated calcium modulator 1 protein_coding Mus_musculus

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