C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transcription factor E3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000134 Tfe3 10090 + X:7762560-7775202 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000077680 Tfe3-003 7762658-7775202 protein_coding
  ENSMUST00000079542 Tfe3-004 7762664-7775199 protein_coding
  ENSMUST00000101695 Tfe3-008 7764041-7775197 protein_coding
  ENSMUST00000115677 Tfe3-002 7763959-7775201 protein_coding
  ENSMUST00000115678 Tfe3-001 7764087-7775199 protein_coding
  ENSMUST00000115679 Tfe3-005 7762676-7775201 protein_coding
  ENSMUST00000115680 Tfe3-010 7762767-7775202 nonsense_mediated_decay
  ENSMUST00000126694 Tfe3-009 7764652-7775197 retained_intron
  ENSMUST00000132209 Tfe3-012 7762586-7766767 processed_transcript
  ENSMUST00000133456 Tfe3-014 7769430-7771318 retained_intron
  ENSMUST00000137467 Tfe3-006 7762695-7775199 protein_coding
  ENSMUST00000143680 Tfe3-007 7762697-7775201 retained_intron
  ENSMUST00000144715 Tfe3-011 7762560-7766071 retained_intron
  ENSMUST00000144900 Tfe3-013 7763943-7766792 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000077680ENSMUST00000079542ENSMUST00000115677ENSMUST00000115678ENSMUST00000115679ENSMUST00000115680ENSMUST00000126694ENSMUST00000143680
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000077680 4.857±0.99 5.021±1.45 3.954±0.68 3.154±0.69 4.913±1.34 5.377±1.08 1.638±0.33 3.693±0.60 2.745±0.59 5.884±0.63 1.186±0.46 3.761±1.04 4.875±1.34 2.220±0.34
ENSMUST00000079542 2.163±0.00 8.042±0.00 N/A N/A N/A N/A 1.094±0.02 0.926±0.00 0.959±0.00 3.127±0.00 0.804±0.00 N/A N/A N/A
ENSMUST00000115677 3.044±0.46 2.741±0.08 N/A N/A 2.295±0.00 2.127±0.00 N/A N/A N/A N/A 1.380±0.52 6.032±2.35 10.522±0.00 2.747±0.00
ENSMUST00000115678 3.856±0.00 6.788±0.80 2.218±0.00 6.178±0.00 3.796±1.46 3.595±0.69 N/A 1.716±0.17 1.428±0.56 4.339±1.89 1.146±0.54 4.399±1.71 5.362±2.34 N/A
ENSMUST00000115679 2.477±0.39 2.876±0.19 2.002±0.78 1.008±0.20 3.285±0.43 2.517±0.72 1.122±0.16 1.880±0.29 1.331±0.45 3.019±0.97 0.541±0.03 2.816±0.54 4.402±1.91 1.179±0.27
ENSMUST00000115680 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.594±0.00 2.441±0.31 2.021±0.00 1.142±0.00
ENSMUST00000126694 N/A N/A 0.466±0.00 0.506±0.04 N/A N/A 0.442±0.01 N/A N/A N/A 0.249±0.01 1.167±0.00 0.460±0.00 0.204±0.13
ENSMUST00000143680 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.480±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005634 IEA nucleus
GO:0005667 IC transcription factor complex
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006959 IEA humoral immune response
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045670 IGI regulation of osteoclast differentiation
GO:0045785 IEA positive regulation of cell adhesion
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0046983 IEA protein dimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004729 tfe3a transcription factor binding to IGHM enhancer 3a protein_coding Danio_rerio
ENSDARG00000019457 tfe3b transcription factor binding to IGHM enhancer 3b protein_coding Danio_rerio
ENSG00000068323 TFE3 transcription factor binding to IGHM enhancer 3 protein_coding Homo_sapiens

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