C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sodium leak channel, non-selective
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000197 Nalcn 10090 - 14:123276641-123627144 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000201 Nalcn-201 123276641-123627144 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000201
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000201 0.117±0.12 1.987±0.47 0.126±0.00 5.546±1.90 0.053±0.02 0.200±0.05 0.153±0.05 0.077±0.02 0.008±0.00 0.128±0.04 0.028±0.01 0.726±0.40 0.013±0.01 0.399±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000WK CIL_0000WK_0002 CGP 14:122918971-123627144
CIL_0004G3 CIL_0004G3_0003 CGP 14:123276641-123975618

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005245 IBA voltage-gated calcium channel activity
GO:0005272 IEA sodium channel activity
GO:0005515 IEA protein binding
GO:0005886 IBA plasma membrane
GO:0016021 IEA integral component of membrane
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0070509 IBA calcium ion import
GO:0070588 IBA calcium ion transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001835 nalcn sodium leak channel, non-selective protein_coding Danio_rerio
ENSG00000102452 NALCN sodium leak channel, non-selective protein_coding Homo_sapiens

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