C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cadherin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000303 Cdh1 10090 + 8:106603351-106670246 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000312 Cdh1-001 106603351-106670246 protein_coding
  ENSMUST00000136580 Cdh1-003 106604143-106653919 processed_transcript
  ENSMUST00000167688 Cdh1-201 106603379-106669362 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000312ENSMUST00000136580ENSMUST00000167688
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000312 11.171±11.13 0.038±0.02 31.639±6.46 0.924±0.53 10.562±0.86 107.316±14.80 0.501±0.34 31.643±1.38 10.583±4.18 55.492±8.91 0.076±0.04 12.024±3.69 48.046±11.40 0.343±0.20
ENSMUST00000136580 0.042±0.00 0.066±0.03 N/A N/A N/A N/A 0.052±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000167688 6.718±4.73 0.048±0.03 N/A 0.080±0.00 9.310±1.32 135.115±16.09 0.368±0.26 12.790±2.16 1.504±0.00 26.017±12.17 0.037±0.00 9.305±1.97 19.057±2.56 0.315±0.27

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004RG CIL_0004RG_0002 CGP 8:106603351-106851439

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0001829 IMP trophectodermal cell differentiation
GO:0001948 IEA glycoprotein binding
GO:0003382 IMP epithelial cell morphogenesis
GO:0005509 IDA calcium ion binding
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005802 IEA trans-Golgi network
GO:0005886 IDA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005912 IDA adherens junction
GO:0005913 IDA cell-cell adherens junction
GO:0005925 IEA focal adhesion
GO:0007156 IEA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007416 IEA synapse assembly
GO:0007605 IMP sensory perception of sound
GO:0008013 IPI beta-catenin binding
GO:0009636 IEA response to toxic substance
GO:0009898 IEA cytoplasmic side of plasma membrane
GO:0009986 IDA cell surface
GO:0010033 IEA response to organic substance
GO:0015629 IEA actin cytoskeleton
GO:0016021 IEA integral component of membrane
GO:0016235 IEA aggresome
GO:0016323 IDA basolateral plasma membrane
GO:0016328 IEA lateral plasma membrane
GO:0016337 IMP single organismal cell-cell adhesion
GO:0016339 IDA calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0016342 IDA catenin complex
GO:0019538 IDA protein metabolic process
GO:0019903 IPI protein phosphatase binding
GO:0019904 IPI protein domain specific binding
GO:0021983 IEA pituitary gland development
GO:0022408 IEA negative regulation of cell-cell adhesion
GO:0030424 IDA axon
GO:0030506 IEA ankyrin binding
GO:0031175 IEA neuron projection development
GO:0032794 IEA GTPase activating protein binding
GO:0032880 IMP regulation of protein localization
GO:0033268 IDA node of Ranvier
GO:0033561 IMP regulation of water loss via skin
GO:0034332 IEA adherens junction organization
GO:0042493 IEA response to drug
GO:0042993 IEA positive regulation of transcription factor import into nucleus
GO:0043219 IDA lateral loop
GO:0043220 IDA Schmidt-Lanterman incisure
GO:0043281 IDA regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043296 IDA apical junction complex
GO:0043679 IDA axon terminus
GO:0045177 IDA apical part of cell
GO:0045295 IEA gamma-catenin binding
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0051260 IDA protein homooligomerization
GO:0060576 IMP intestinal epithelial cell development
GO:0060662 IMP salivary gland cavitation
GO:0060693 IMP regulation of branching involved in salivary gland morphogenesis
GO:0070062 IEA extracellular vesicular exosome
GO:0070830 IMP tight junction assembly
GO:0071230 IDA cellular response to amino acid stimulus
GO:0071285 IEA cellular response to lithium ion
GO:0071681 IEA cellular response to indole-3-methanol
GO:0071944 IDA cell periphery
GO:0072659 IEA protein localization to plasma membrane
GO:0090002 IDA establishment of protein localization to plasma membrane
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway
GO:0090102 IMP cochlea development
GO:2000008 IMP regulation of protein localization to cell surface
GO:2001222 IDA regulation of neuron migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024371 cdh1 cadherin 1, epithelial protein_coding Danio_rerio
ENSDARG00000035796 si:ch211-206i14.2 si:ch211-206i14.2 protein_coding Danio_rerio
ENSDARG00000058546 si:dkey-30c15.12 si:dkey-30c15.12 protein_coding Danio_rerio
ENSDARG00000068137 si:dkey-173l11.5 si:dkey-173l11.5 protein_coding Danio_rerio
ENSDARG00000092450 si:dkey-173l11.3 si:dkey-173l11.3 protein_coding Danio_rerio
ENSG00000039068 CDH1 cadherin 1, type 1, E-cadherin (epithelial) protein_coding Homo_sapiens

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