C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin alpha 5 (fibronectin receptor alpha)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000555 Itga5 10090 - 15:103344289-103366763 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023128 Itga5-201 103344289-103366763 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023128
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023128 16.292±5.94 14.276±0.84 53.156±10.07 1.797±0.77 8.834±1.81 22.205±2.56 11.804±1.60 2.614±0.88 8.274±1.32 13.043±1.78 1.853±0.49 18.560±5.15 48.649±21.19 0.256±0.19

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000031 CIL_000031_0002 CGP 15:103313895-103366763
CIL_00003E CIL_00003E_0002 CGP 15:103344289-103430470

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005154 IEA epidermal growth factor receptor binding
GO:0005178 IPI integrin binding
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005911 IEA cell-cell junction
GO:0005925 IEA focal adhesion
GO:0007044 IDA cell-substrate junction assembly
GO:0007155 IEA cell adhesion
GO:0007157 IMP heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007159 IMP leukocyte cell-cell adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0007613 IMP memory
GO:0008305 IEA integrin complex
GO:0009897 IDA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0010811 IEA positive regulation of cell-substrate adhesion
GO:0030335 IEA positive regulation of cell migration
GO:0031589 IEA cell-substrate adhesion
GO:0032587 IEA ruffle membrane
GO:0033631 IMP cell-cell adhesion mediated by integrin
GO:0034113 IEA heterotypic cell-cell adhesion
GO:0035313 IEA wound healing, spreading of epidermal cells
GO:0035987 IEA endodermal cell differentiation
GO:0045202 IDA synapse
GO:0046872 IEA metal ion binding
GO:0050731 IEA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050839 IEA cell adhesion molecule binding
GO:2000811 IEA negative regulation of anoikis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006353 itga5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) protein_coding Danio_rerio
ENSG00000161638 ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) protein_coding Homo_sapiens

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