C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: WD repeat domain 77
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000561 Wdr77 10090 + 3:105959369-105984600 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000010278 Wdr77-001 105959369-105969760 protein_coding
  ENSMUST00000127464 Wdr77-003 105959508-105966092 retained_intron
  ENSMUST00000128005 Wdr77-006 105961622-105967527 protein_coding
  ENSMUST00000130994 Wdr77-002 105959514-105970037 nonsense_mediated_decay
  ENSMUST00000137168 Wdr77-004 105966115-105976411 retained_intron
  ENSMUST00000151263 Wdr77-005 105964449-105965551 retained_intron
  ENSMUST00000167642 Wdr77-007 105959503-105984600 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonLiverLungPlacentaTestisENSMUST00000010278ENSMUST00000128005ENSMUST00000167642
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Liver Lung Placenta Testis
ENSMUST00000010278 15.052±4.58 27.233±1.30 10.254±0.99 12.238±4.44 12.750±1.65 9.469±0.52 11.384±0.91 11.445±0.63 13.185±3.59 10.816±0.00
ENSMUST00000128005 24.438±3.22 N/A N/A N/A 44.203±0.00 N/A N/A N/A N/A N/A
ENSMUST00000167642 N/A N/A N/A N/A N/A N/A N/A N/A N/A 23.145±5.25

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005829 ISS cytosol
GO:0006357 IMP regulation of transcription from RNA polymerase II promoter
GO:0008284 IGI positive regulation of cell proliferation
GO:0008285 IGI negative regulation of cell proliferation
GO:0030374 IEA ligand-dependent nuclear receptor transcription coactivator activity
GO:0034709 ISS methylosome
GO:0060528 IMP secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
GO:0060770 IMP negative regulation of epithelial cell proliferation involved in prostate gland development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089591 WDR77 WD repeat domain 77 protein_coding Danio_rerio
ENSG00000116455 WDR77 WD repeat domain 77 protein_coding Homo_sapiens

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