C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: seizure related gene 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000632 Sez6 10090 + 11:77930800-77979048 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000646 Sez6-009 77931012-77979040 protein_coding
  ENSMUST00000093995 Sez6-001 77930800-77979048 protein_coding
  ENSMUST00000126866 Sez6-006 77973173-77974374 retained_intron
  ENSMUST00000138346 Sez6-002 77951305-77954762 processed_transcript
  ENSMUST00000138749 Sez6-008 77930917-77964091 retained_intron
  ENSMUST00000140630 Sez6-003 77969011-77974488 protein_coding
  ENSMUST00000142542 Sez6-005 77930839-77979048 retained_intron
  ENSMUST00000151982 Sez6-007 77953853-77979048 nonsense_mediated_decay
  ENSMUST00000155087 Sez6-004 77931039-77978061 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000646ENSMUST00000093995ENSMUST00000126866ENSMUST00000138346ENSMUST00000138749ENSMUST00000140630ENSMUST00000142542ENSMUST00000151982ENSMUST00000155087
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000646 N/A N/A 0.011±0.00 14.927±2.68 N/A 0.060±0.02 N/A 0.028±0.02 N/A 0.014±0.00 0.107±0.01 0.351±0.25 0.010±0.00 N/A
ENSMUST00000093995 N/A 0.241±0.11 N/A 39.141±2.51 N/A 0.139±0.04 N/A N/A 0.004±0.00 N/A N/A 0.616±0.18 N/A N/A
ENSMUST00000126866 N/A N/A N/A N/A N/A N/A 0.195±0.00 N/A 0.016±0.00 N/A 0.148±0.00 N/A N/A N/A
ENSMUST00000138346 N/A N/A N/A N/A N/A N/A N/A 0.027±0.00 0.013±0.00 N/A N/A N/A N/A N/A
ENSMUST00000138749 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.019±0.00 N/A
ENSMUST00000140630 N/A N/A N/A 25.009±0.00 0.135±0.00 N/A 0.153±0.00 N/A N/A N/A 0.076±0.00 0.721±0.00 N/A 0.566±0.00
ENSMUST00000142542 0.309±0.00 N/A N/A 12.433±2.93 0.066±0.00 N/A N/A N/A N/A N/A 0.044±0.00 0.198±0.06 N/A N/A
ENSMUST00000151982 0.859±0.66 0.260±0.09 0.022±0.00 12.381±2.13 0.198±0.08 0.210±0.12 0.062±0.03 0.033±0.01 0.015±0.01 0.055±0.01 0.075±0.05 0.508±0.22 0.017±0.00 N/A
ENSMUST00000155087 N/A N/A N/A N/A 0.043±0.00 0.130±0.08 N/A N/A 0.005±0.00 N/A 0.094±0.00 0.163±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00076L CIL_00076L_0003 CGP 11:77880615-77979048
CIL_0006M6 CIL_0006M6_0002 CGP 11:77930800-78030539

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005615 IDA extracellular space
GO:0005783 IDA endoplasmic reticulum
GO:0005886 IEA plasma membrane
GO:0008344 IGI adult locomotory behavior
GO:0016021 IEA integral component of membrane
GO:0021680 IGI cerebellar Purkinje cell layer development
GO:0030054 IEA cell junction
GO:0043025 IDA neuronal cell body
GO:0043197 IDA dendritic spine
GO:0043198 IDA dendritic shaft
GO:0045202 IEA synapse
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050773 IMP regulation of dendrite development
GO:0060074 IGI synapse maturation
GO:0060079 IMP regulation of excitatory postsynaptic membrane potential
GO:0090036 IGI regulation of protein kinase C signaling
GO:0097440 IDA apical dendrite
GO:1900006 IDA positive regulation of dendrite development
GO:2000171 IDA negative regulation of dendrite development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076220 sez6a seizure related 6 homolog a protein_coding Danio_rerio
ENSDARG00000079414 sez6b seizure related 6 homolog b protein_coding Danio_rerio
ENSG00000063015 SEZ6 seizure related 6 homolog (mouse) protein_coding Homo_sapiens

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