C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine (or cysteine) peptidase inhibitor, clade F, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000753 Serpinf1 10090 - 11:75409769-75422701 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000769 Serpinf1-001 75409769-75422701 protein_coding
  ENSMUST00000125982 Serpinf1-005 75415470-75422552 protein_coding
  ENSMUST00000137103 Serpinf1-006 75414921-75422555 protein_coding
  ENSMUST00000138661 Serpinf1-002 75413914-75422586 protein_coding
  ENSMUST00000139403 Serpinf1-004 75413973-75415195 retained_intron
  ENSMUST00000155009 Serpinf1-003 75416316-75418297 protein_coding
  ENSMUST00000167281 Serpinf1-008 75410221-75415730 nonsense_mediated_decay
  ENSMUST00000168902 Serpinf1-007 75410064-75417996 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000769ENSMUST00000125982ENSMUST00000137103ENSMUST00000167281ENSMUST00000168902
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000769 35.275±10.35 3.882±0.98 8.030±0.96 0.646±0.13 40.789±16.55 3.145±0.91 4.508±1.05 1.592±0.68 68.167±42.97 7.014±0.89 7.622±1.67 18.909±5.93 1.584±1.41 1.042±0.26
ENSMUST00000125982 78.412±24.18 12.619±5.42 19.450±3.62 2.982±0.85 190.962±23.74 5.558±0.55 11.785±0.66 3.868±1.55 79.649±38.11 20.035±3.17 N/A 73.139±15.71 7.046±2.53 2.635±0.45
ENSMUST00000137103 N/A N/A N/A N/A 28.994±0.00 N/A N/A N/A N/A N/A 7.421±1.45 N/A 1.041±0.47 N/A
ENSMUST00000167281 N/A N/A 15.653±0.00 2.402±0.00 55.396±0.00 N/A N/A 1.177±0.30 14.856±0.00 N/A N/A 45.942±6.16 1.264±0.57 0.917±0.27
ENSMUST00000168902 39.389±11.50 N/A 20.493±4.00 2.560±1.22 55.914±21.60 N/A 6.814±1.89 1.113±0.38 48.727±13.61 N/A 19.177±2.25 79.581±10.74 3.098±3.26 0.830±0.13

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001822 IEA kidney development
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005576 IDA extracellular region
GO:0005604 IEA basement membrane
GO:0005615 IDA extracellular space
GO:0007568 IEA aging
GO:0007614 IEA short-term memory
GO:0010447 IEA response to acidity
GO:0010596 IEA negative regulation of endothelial cell migration
GO:0010629 IEA negative regulation of gene expression
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0010976 IEA positive regulation of neuron projection development
GO:0016525 IDA negative regulation of angiogenesis
GO:0030162 IBA regulation of proteolysis
GO:0030424 IEA axon
GO:0031012 IEA extracellular matrix
GO:0042698 IEA ovulation cycle
GO:0043025 IEA neuronal cell body
GO:0043203 IEA axon hillock
GO:0046685 IEA response to arsenic-containing substance
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050728 IEA negative regulation of inflammatory response
GO:0050769 ISS positive regulation of neurogenesis
GO:0060041 IEA retina development in camera-type eye
GO:0060770 IMP negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0070062 IEA extracellular vesicular exosome
GO:0071279 IEA cellular response to cobalt ion
GO:0071300 IEA cellular response to retinoic acid
GO:0071333 IEA cellular response to glucose stimulus
GO:0071549 IEA cellular response to dexamethasone stimulus
GO:1901215 IEA negative regulation of neuron death

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069048 serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1 protein_coding Danio_rerio
ENSG00000132386 SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 protein_coding Homo_sapiens

Loading