C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: opioid receptor, mu 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000766 Oprm1 10090 + 10:6758506-7038198 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000783 Oprm1-017 6788809-6838680 protein_coding
  ENSMUST00000052751 Oprm1-030 6788809-7037201 protein_coding
  ENSMUST00000056385 Oprm1-007 6758593-6849858 protein_coding
  ENSMUST00000063036 Oprm1-029 6758593-7037546 protein_coding
  ENSMUST00000078634 Oprm1-016 6788809-6832987 protein_coding
  ENSMUST00000092729 Oprm1-014 6788809-6841362 nonsense_mediated_decay
  ENSMUST00000092731 Oprm1-013 6788809-6839919 protein_coding
  ENSMUST00000092734 Oprm1-008 6758593-6849858 protein_coding
  ENSMUST00000105597 Oprm1-004 6758593-6849858 nonsense_mediated_decay
  ENSMUST00000105601 Oprm1-009 6788694-7037177 nonsense_mediated_decay
  ENSMUST00000105602 Oprm1-011 6788809-6830639 protein_coding
  ENSMUST00000105603 Oprm1-018 6788837-6832793 protein_coding
  ENSMUST00000105604 Oprm1-019 6788837-6839954 protein_coding
  ENSMUST00000105605 Oprm1-015 6788809-6841537 protein_coding
  ENSMUST00000105607 Oprm1-003 6758593-6850613 protein_coding
  ENSMUST00000105611 Oprm1-026 6788809-7038198 protein_coding
  ENSMUST00000105615 Oprm1-002 6758506-7037201 protein_coding
  ENSMUST00000123861 Oprm1-028 6788809-6979764 nonsense_mediated_decay
  ENSMUST00000129221 Oprm1-023 6788809-7037462 nonsense_mediated_decay
  ENSMUST00000129954 Oprm1-012 6788809-7037177 nonsense_mediated_decay
  ENSMUST00000133486 Oprm1-020 6789025-6828911 processed_transcript
  ENSMUST00000135502 Oprm1-027 6788809-6979754 protein_coding
  ENSMUST00000141897 Oprm1-022 6788975-7037482 processed_transcript
  ENSMUST00000143875 Oprm1-006 6758593-6828964 nonsense_mediated_decay
  ENSMUST00000144264 Oprm1-024 6788809-7037482 nonsense_mediated_decay
  ENSMUST00000147171 Oprm1-001 6758506-6979704 nonsense_mediated_decay
  ENSMUST00000148625 Oprm1-021 6789099-6849987 processed_transcript
  ENSMUST00000150374 Oprm1-005 6758593-6849858 nonsense_mediated_decay
  ENSMUST00000152674 Oprm1-031 6788601-6850348 protein_coding
  ENSMUST00000154906 Oprm1-010 6788809-6841380 protein_coding
  ENSMUST00000154941 Oprm1-025 6788809-7037198 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainColonHeartPlacentaTestisENSMUST00000052751ENSMUST00000063036ENSMUST00000078634ENSMUST00000092731ENSMUST00000105601ENSMUST00000105604ENSMUST00000105607ENSMUST00000105611ENSMUST00000141897ENSMUST00000143875ENSMUST00000147171ENSMUST00000150374ENSMUST00000152674
Transcript ID Adrenal Brain Colon Heart Placenta Testis
ENSMUST00000052751 0.056±0.00 N/A N/A N/A N/A N/A
ENSMUST00000063036 N/A N/A N/A N/A N/A 0.013±0.00
ENSMUST00000078634 N/A N/A N/A N/A N/A 0.049±0.00
ENSMUST00000092731 0.071±0.00 N/A N/A N/A N/A N/A
ENSMUST00000105601 N/A N/A 0.262±0.00 N/A N/A N/A
ENSMUST00000105604 0.113±0.00 N/A N/A N/A 0.025±0.00 N/A
ENSMUST00000105607 N/A 0.522±0.00 0.136±0.00 N/A N/A N/A
ENSMUST00000105611 N/A N/A N/A N/A N/A 0.026±0.00
ENSMUST00000141897 N/A N/A N/A 0.028±0.00 N/A 0.041±0.00
ENSMUST00000143875 0.169±0.00 N/A N/A N/A N/A N/A
ENSMUST00000147171 0.043±0.00 N/A N/A N/A N/A N/A
ENSMUST00000150374 0.131±0.00 N/A 0.272±0.08 N/A N/A 0.027±0.00
ENSMUST00000152674 N/A N/A 0.118±0.00 N/A 0.034±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00055K CIL_00055K_0002 CGP 10:6758506-7052478

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001965 ISS G-protein alpha-subunit binding
GO:0002438 IEA acute inflammatory response to antigenic stimulus
GO:0004930 ISS G-protein coupled receptor activity
GO:0004979 IEA beta-endorphin receptor activity
GO:0004985 IDA opioid receptor activity
GO:0005245 ISS voltage-gated calcium channel activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0005925 IEA focal adhesion
GO:0007191 IDA adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007193 IDA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007194 ISS negative regulation of adenylate cyclase activity
GO:0007200 ISS phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007218 IEA neuropeptide signaling pathway
GO:0007626 IMP locomotory behavior
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0019233 IMP sensory perception of pain
GO:0019904 IEA protein domain specific binding
GO:0030425 IEA dendrite
GO:0031005 IEA filamin binding
GO:0031635 IEA adenylate cyclase-inhibiting opioid receptor signaling pathway
GO:0031681 IEA G-protein beta-subunit binding
GO:0032094 IEA response to food
GO:0032100 IEA positive regulation of appetite
GO:0032496 IEA response to lipopolysaccharide
GO:0032590 IEA dendrite membrane
GO:0032839 IEA dendrite cytoplasm
GO:0033554 IEA cellular response to stress
GO:0038003 IEA opioid receptor signaling pathway
GO:0038047 ISS morphine receptor activity
GO:0042060 IEA wound healing
GO:0042220 IEA response to cocaine
GO:0042383 IEA sarcolemma
GO:0043204 IEA perikaryon
GO:0043278 IEA response to morphine
GO:0043950 IEA positive regulation of cAMP-mediated signaling
GO:0043951 ISS negative regulation of cAMP-mediated signaling
GO:0045019 ISS negative regulation of nitric oxide biosynthetic process
GO:0045121 IEA membrane raft
GO:0045429 IEA positive regulation of nitric oxide biosynthetic process
GO:0048149 IEA behavioral response to ethanol
GO:0050769 IMP positive regulation of neurogenesis
GO:0051481 ISS negative regulation of cytosolic calcium ion concentration
GO:0051930 IEA regulation of sensory perception of pain
GO:0060079 IEA regulation of excitatory postsynaptic membrane potential
GO:0061358 ISS negative regulation of Wnt protein secretion
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:0070588 ISS calcium ion transmembrane transport
GO:0070848 IEA response to growth factor
GO:0071315 IEA cellular response to morphine
GO:2000310 ISS regulation of N-methyl-D-aspartate selective glutamate receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039434 oprm1 opioid receptor, mu 1 protein_coding Danio_rerio
ENSG00000112038 OPRM1 opioid receptor, mu 1 protein_coding Homo_sapiens

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