C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: carbonic anhydrase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000805 Car4 10090 + 11:84957786-84966044 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000103194 Car4-001 84957788-84966044 protein_coding
  ENSMUST00000108076 Car4-005 84964347-84966044 protein_coding
  ENSMUST00000127827 Car4-002 84958104-84964228 nonsense_mediated_decay
  ENSMUST00000138331 Car4-006 84957811-84961918 processed_transcript
  ENSMUST00000139416 Car4-004 84957786-84962555 retained_intron
  ENSMUST00000150596 Car4-003 84957825-84964563 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000103194ENSMUST00000108076ENSMUST00000127827ENSMUST00000138331ENSMUST00000139416ENSMUST00000150596
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000103194 16.894±12.01 2.436±0.50 0.279±0.13 4.012±4.70 6.440±1.76 300.715±15.07 9.313±1.10 42.295±1.59 0.089±0.08 80.739±4.01 2.399±0.94 0.898±0.68 199.892±72.79 1.485±0.54
ENSMUST00000108076 N/A N/A N/A 17.333±0.00 N/A N/A N/A N/A 0.033±0.02 N/A N/A 0.596±0.04 220.450±113.63 3.781±0.00
ENSMUST00000127827 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.391±0.00 N/A N/A
ENSMUST00000138331 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.441±0.03 N/A N/A
ENSMUST00000139416 N/A 0.761±0.14 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000150596 N/A N/A 0.117±0.00 36.892±0.00 N/A N/A N/A N/A 0.021±0.00 N/A N/A 0.755±0.00 369.030±0.00 16.798±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007YB CIL_0007YB_0004 VISTA 11:84425827-85026602
CIL_00085R CIL_00085R_0002 VISTA 11:84466073-85066769
CIL_0006V1 CIL_0006V1_0002 CGP 11:84957786-85140161

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004089 IDA carbonate dehydratase activity
GO:0005515 IPI protein binding
GO:0005791 IEA rough endoplasmic reticulum
GO:0005793 IEA endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 IEA Golgi apparatus
GO:0005802 IEA trans-Golgi network
GO:0005886 IEA plasma membrane
GO:0006730 IEA one-carbon metabolic process
GO:0006885 IC regulation of pH
GO:0008152 IDA metabolic process
GO:0008270 IEA zinc ion binding
GO:0009986 IEA cell surface
GO:0015670 IC carbon dioxide transport
GO:0015701 IEA bicarbonate transport
GO:0016020 IDA membrane
GO:0016324 IEA apical plasma membrane
GO:0016529 IEA sarcoplasmic reticulum
GO:0030658 IEA transport vesicle membrane
GO:0030667 IEA secretory granule membrane
GO:0031362 IEA anchored component of external side of plasma membrane
GO:0031526 IEA brush border membrane
GO:0042383 IEA sarcolemma
GO:0042493 IEA response to drug
GO:0046658 IDA anchored component of plasma membrane
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048513 IEA organ development
GO:0048545 IEA response to steroid hormone
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002259 ca15c carbonic anhydrase XV c protein_coding Danio_rerio
ENSDARG00000015654 ca15a carbonic anhydrase XV a protein_coding Danio_rerio
ENSDARG00000040510 ca15b carbonic anhydrase XV b protein_coding Danio_rerio
ENSDARG00000074666 CA4 (4 of 5) carbonic anhydrase IV protein_coding Danio_rerio
ENSDARG00000087756 CA4 (5 of 5) carbonic anhydrase IV protein_coding Danio_rerio
ENSG00000167434 CA4 carbonic anhydrase IV protein_coding Homo_sapiens

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