C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Fas ligand (TNF superfamily, member 6)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000817 Fasl 10090 - 1:161780691-161788495 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000834 Fasl-201 161780691-161788495 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000834
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000834 0.093±0.08 0.081±0.02 0.107±0.02 0.092±0.01 0.403±0.24 0.087±0.06 0.042±0.03 0.068±0.04 0.085±0.04 0.258±0.07 0.018±0.01 0.040±0.03 0.570±0.54 0.202±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007X6 CIL_0007X6_0002 VISTA 1:161774031-162377560

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0005123 IEA death receptor binding
GO:0005125 IEA cytokine activity
GO:0005615 IEA extracellular space
GO:0005634 ISS nucleus
GO:0005764 IEA lysosome
GO:0005901 IEA caveola
GO:0006351 IEA transcription, DNA-templated
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006925 IEA inflammatory cell apoptotic process
GO:0006955 IEA immune response
GO:0008284 IEA positive regulation of cell proliferation
GO:0008625 IDA extrinsic apoptotic signaling pathway via death domain receptors
GO:0009897 IDA external side of plasma membrane
GO:0016021 IEA integral component of membrane
GO:0016023 IEA cytoplasmic membrane-bounded vesicle
GO:0016525 IEA negative regulation of angiogenesis
GO:0030644 IEA cellular chloride ion homeostasis
GO:0032496 IEA response to lipopolysaccharide
GO:0043065 ISO positive regulation of apoptotic process
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0045121 IEA membrane raft
GO:0045742 IEA positive regulation of epidermal growth factor receptor signaling pathway
GO:0046666 IMP retinal cell programmed cell death
GO:0048388 IEA endosomal lumen acidification
GO:0048471 IEA perinuclear region of cytoplasm
GO:0070062 IEA extracellular vesicular exosome
GO:0070231 IEA T cell apoptotic process
GO:0070266 IEA necroptotic process
GO:0070848 IEA response to growth factor
GO:0097190 IDA apoptotic signaling pathway
GO:0097191 IEA extrinsic apoptotic signaling pathway
GO:0097527 IEA necroptotic signaling pathway
GO:2000353 IEA positive regulation of endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011520 faslg Fas ligand (TNF superfamily, member 6) protein_coding Danio_rerio
ENSG00000117560 FASLG Fas ligand (TNF superfamily, member 6) protein_coding Homo_sapiens

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