C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: B cell CLL/lymphoma 11A (zinc finger protein)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000861 Bcl11a 10090 + 11:24078056-24174123 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000881 Bcl11a-003 24078056-24173194 protein_coding
  ENSMUST00000109514 Bcl11a-006 24078173-24168429 protein_coding
  ENSMUST00000109516 Bcl11a-005 24078117-24174123 protein_coding
  ENSMUST00000118955 Bcl11a-001 24080670-24173558 protein_coding
  ENSMUST00000124148 Bcl11a-004 24078147-24090906 retained_intron
  ENSMUST00000127494 Bcl11a-002 24142379-24163291 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000881ENSMUST00000109514ENSMUST00000118955ENSMUST00000124148ENSMUST00000127494
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000881 0.055±0.02 0.261±0.10 0.306±0.07 12.993±1.51 1.433±0.83 0.566±0.18 0.195±0.05 0.122±0.08 2.796±2.12 0.267±0.05 0.354±0.00 1.214±0.43 0.102±0.05 1.595±0.37
ENSMUST00000109514 0.010±0.00 0.325±0.09 0.076±0.01 8.852±4.60 1.290±0.15 0.371±0.12 0.052±0.01 0.057±0.02 1.695±1.72 0.112±0.02 0.081±0.13 1.017±0.46 0.060±0.05 N/A
ENSMUST00000118955 0.024±0.00 0.300±0.07 N/A 11.734±0.00 0.870±0.00 0.604±0.12 0.205±0.06 0.100±0.01 4.143±2.14 0.388±0.00 N/A 1.359±0.00 0.050±0.00 N/A
ENSMUST00000124148 0.049±0.04 N/A 0.119±0.02 4.019±0.78 0.530±0.15 0.172±0.00 0.071±0.02 0.035±0.01 1.129±0.93 0.129±0.03 0.069±0.00 0.390±0.00 0.026±0.02 N/A
ENSMUST00000127494 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.130±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PG CIL_0008PG_0002 VISTA 11:23715166-24317101
CIL_0009DA CIL_0009DA_0002 VISTA 11:23762086-24363576
CIL_0008GM CIL_0008GM_0002 VISTA 11:23795054-24396665
CIL_0008WW CIL_0008WW_0002 VISTA 11:24012332-24614280
CIL_000881 CIL_000881_0002 VISTA 11:24029867-24633908
CIL_0007LM CIL_0007LM_0002 UCNEbase 11:24062983-26981636
CIL_0008BH CIL_0008BH_0002 VISTA 11:24070835-24671855

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003676 IEA nucleic acid binding
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0010629 IMP negative regulation of gene expression
GO:0010976 IEA positive regulation of neuron projection development
GO:0010977 IEA negative regulation of neuron projection development
GO:0016604 IDA nuclear body
GO:0016925 IMP protein sumoylation
GO:0030183 IMP B cell differentiation
GO:0030217 IMP T cell differentiation
GO:0046872 IEA metal ion binding
GO:0046982 IEA protein heterodimerization activity
GO:0048671 IEA negative regulation of collateral sprouting
GO:0048672 IEA positive regulation of collateral sprouting
GO:0050773 IEA regulation of dendrite development
GO:2000171 IEA negative regulation of dendrite development
GO:2001141 IDA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061352 bcl11aa B-cell CLL/lymphoma 11Aa protein_coding Danio_rerio
ENSDARG00000063153 bcl11ab B-cell CLL/lymphoma 11Ab protein_coding Danio_rerio
ENSG00000119866 BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) protein_coding Homo_sapiens

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