C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DNA topoisomerase 1, mitochondrial
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000934 Top1mt 10090 - 15:75657035-75678800 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000958 Top1mt-001 75657035-75678800 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000958
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000958 4.058±0.97 3.152±1.71 8.475±0.33 7.671±4.40 1.331±0.49 1.361±0.53 1.407±0.35 8.509±1.33 8.774±2.49 1.834±0.40 5.206±0.99 4.921±3.77 15.258±10.22 5.503±4.51

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008C2 CIL_0008C2_0002 VISTA 15:75534812-76135772
CIL_0001NH CIL_0001NH_0002 CGP 15:75657035-75714410

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003917 IBA DNA topoisomerase type I activity
GO:0003918 IEA DNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0005634 IEA nucleus
GO:0005694 IEA chromosome
GO:0005739 IDA mitochondrion
GO:0006200 IEA ATP catabolic process
GO:0006260 IBA DNA replication
GO:0006265 IBA DNA topological change
GO:0042645 IBA mitochondrial nucleoid

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055959 CABZ01090980.1 Uncharacterized protein protein_coding Danio_rerio
ENSG00000184428 TOP1MT topoisomerase (DNA) I, mitochondrial protein_coding Homo_sapiens

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