Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	cytochrome P450, family 51
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSMUSG00000001467	Cyp51	10090	-	5:4081145-4104746	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENSMUST00000001507		Cyp51-001	4081145-4104746	protein_coding
	ENSMUST00000129448		Cyp51-002	4083280-4104343	processed_transcript
	ENSMUST00000151539		Cyp51-003	4099124-4103381	retained_intron

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENSMUST00000001507	7.350±0.53	29.620±4.46	2.286±0.77	20.910±12.21	8.062±4.29	19.617±2.33	1.505±0.24	36.916±10.19	22.173±14.19	8.827±0.57	0.703±0.19	18.465±2.99	9.140±4.97	16.533±2.65
ENSMUST00000129448	N/A	N/A	N/A	18.032±0.00	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	7.561±0.00	N/A

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_0006E3	CIL_0006E3_0002	CGP	5:3928054-4104746

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0005506	IEA	iron ion binding
GO:0005783	IEA	endoplasmic reticulum
GO:0006694	ISS	steroid biosynthetic process
GO:0006695	TAS	cholesterol biosynthetic process
GO:0008398	ISS	sterol 14-demethylase activity
GO:0016020	IEA	membrane
GO:0016021	IEA	integral component of membrane
GO:0020037	ISS	heme binding
GO:0033488	IEA	cholesterol biosynthetic process via 24,25-dihydrolanosterol
GO:0043231	IEA	intracellular membrane-bounded organelle
GO:0055114	IEA	oxidation-reduction process
GO:0070988	IEA	demethylation

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000042641	cyp51	cytochrome P450, family 51	protein_coding	Danio_rerio
ENSG00000001630	CYP51A1	cytochrome P450, family 51, subfamily A, polypeptide 1	protein_coding	Homo_sapiens

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