C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, ionotropic, NMDA2D (epsilon 4)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000002771 Grin2d 10090 - 7:45831883-45870928 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000002848 Grin2d-001 45831883-45867129 protein_coding
  ENSMUST00000146672 Grin2d-002 45866377-45870928 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000002848
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000002848 1.271±0.18 0.210±0.06 1.302±0.19 6.764±4.39 0.276±0.05 0.610±0.26 0.135±0.05 0.125±0.08 0.079±0.05 0.609±0.42 0.067±0.03 0.984±0.50 0.333±0.14 7.086±1.55

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001964 IMP startle response
GO:0004972 IMP N-methyl-D-aspartate selective glutamate receptor activity
GO:0005234 IBA extracellular-glutamate-gated ion channel activity
GO:0005515 IEA protein binding
GO:0008344 IMP adult locomotory behavior
GO:0017146 IBA N-methyl-D-aspartate selective glutamate receptor complex
GO:0030054 IEA cell junction
GO:0030425 IBA dendrite
GO:0034220 IBA:IEA ion transmembrane transport
GO:0035235 IMP:IEA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0045202 IDA synapse
GO:0045211 IBA postsynaptic membrane
GO:0051930 IMP regulation of sensory perception of pain

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070620 grin2db glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b protein_coding Danio_rerio
ENSDARG00000086207 grin2da glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a protein_coding Danio_rerio
ENSG00000105464 GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D protein_coding Homo_sapiens

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