C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear factor of activated T cells 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000003847 Nfat5 10090 + 8:107293470-107379517 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000075922 Nfat5-002 107293559-107379508 protein_coding
  ENSMUST00000077440 Nfat5-201 107338807-107379516 protein_coding
  ENSMUST00000125721 Nfat5-005 107293559-107372178 protein_coding
  ENSMUST00000126333 Nfat5-011 107344786-107361770 nonsense_mediated_decay
  ENSMUST00000126397 Nfat5-008 107338508-107367405 retained_intron
  ENSMUST00000133026 Nfat5-001 107293470-107379517 nonsense_mediated_decay
  ENSMUST00000144100 Nfat5-012 107338913-107370659 protein_coding
  ENSMUST00000147588 Nfat5-010 107355820-107373530 protein_coding
  ENSMUST00000148006 Nfat5-009 107338508-107355740 retained_intron
  ENSMUST00000149972 Nfat5-006 107293509-107327991 retained_intron
  ENSMUST00000151114 Nfat5-004 107293509-107370659 protein_coding
  ENSMUST00000151582 Nfat5-003 107293470-107329307 retained_intron
  ENSMUST00000154474 Nfat5-007 107293470-107372227 nonsense_mediated_decay
  ENSMUST00000169453 Nfat5-202 107293470-107379516 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000077440ENSMUST00000133026ENSMUST00000147588ENSMUST00000151114ENSMUST00000169453
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000077440 1.288±0.00 N/A 17.786±2.81 3.927±3.07 2.213±0.12 N/A 1.265±0.44 3.254±0.42 1.909±0.50 N/A 0.959±0.18 10.906±6.36 3.991±2.50 1.532±0.73
ENSMUST00000133026 6.157±3.80 10.364±1.49 3.746±0.35 1.744±0.40 5.060±1.18 3.134±1.28 1.999±0.15 4.480±1.81 1.435±0.51 8.481±3.19 0.591±0.08 7.071±2.89 2.309±0.29 2.566±1.84
ENSMUST00000147588 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.108±2.29 0.572±0.00
ENSMUST00000151114 N/A 8.991±1.02 N/A N/A 3.927±0.54 2.064±0.00 N/A N/A N/A N/A N/A N/A N/A 0.780±0.00
ENSMUST00000169453 2.906±1.09 12.184±2.67 N/A 1.568±0.14 3.817±1.39 2.278±0.86 1.953±0.32 2.887±0.92 1.026±0.17 4.798±0.86 N/A 8.023±2.53 1.519±0.35 1.764±0.61

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008KB CIL_0008KB_0002 VISTA 8:107038845-107639359
CIL_0004I1 CIL_0004I1_0002 CGP 8:107293470-107403206

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001816 IDA cytokine production
GO:0003677 IDA DNA binding
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 ISS transcription, DNA-templated
GO:0010628 IDA positive regulation of gene expression
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0070884 IDA regulation of calcineurin-NFAT signaling cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014022 NFAT5 (1 of 2) nuclear factor of activated T-cells 5, tonicity-responsive protein_coding Danio_rerio
ENSDARG00000020872 nfat5 nuclear factor of activated T-cells 5, tonicity-responsive protein_coding Danio_rerio
ENSG00000102908 NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive protein_coding Homo_sapiens

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