C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: N-myc downstream regulated gene 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004558 Ndrg2 10090 - 14:51905271-51913488 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000004673 Ndrg2-201 51905271-51913488 protein_coding
  ENSMUST00000111632 Ndrg2-202 51905271-51913488 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000004673ENSMUST00000111632
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000004673 36.501±8.30 136.395±7.91 95.423±19.51 3.927±0.56 101.839±54.52 73.247±3.96 332.207±37.04 47.678±2.12 457.570±437.47 36.358±3.71 381.936±21.66 32.546±10.61 1.923±0.20 5.364±1.25
ENSMUST00000111632 12.918±2.27 47.643±11.61 31.112±10.66 22.150±4.07 13.534±0.94 17.577±3.82 88.353±15.88 7.520±0.48 12.472±11.15 17.837±3.24 N/A 44.530±16.20 1.698±1.08 1.534±0.38

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004TH CIL_0004TH_0002 CGP 14:51892889-51913488
CIL_00027R CIL_00027R_0002 CGP 14:51905271-51920699

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001818 IMP negative regulation of cytokine production
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005813 IEA centrosome
GO:0005815 IEA microtubule organizing center
GO:0007165 IEA signal transduction
GO:0010574 IMP regulation of vascular endothelial growth factor production
GO:0016055 IEA Wnt signaling pathway
GO:0021762 IEA substantia nigra development
GO:0030154 IEA cell differentiation
GO:0042995 IEA cell projection
GO:0048662 IDA negative regulation of smooth muscle cell proliferation
GO:0070062 IEA extracellular vesicular exosome
GO:0070373 IMP negative regulation of ERK1 and ERK2 cascade
GO:0090361 IMP regulation of platelet-derived growth factor production

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011170 ndrg2 N-myc downstream regulated gene 2 protein_coding Danio_rerio
ENSG00000165795 NDRG2 NDRG family member 2 protein_coding Homo_sapiens

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