C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase N2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004591 Pkn2 10090 - 3:142790902-142882004 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000043812 Pkn2-001 142790902-142882004 protein_coding
  ENSMUST00000166330 Pkn2-003 142799952-142881920 processed_transcript
  ENSMUST00000172521 Pkn2-002 142804789-142881990 processed_transcript
  ENSMUST00000172916 Pkn2-004 142830238-142881983 retained_intron
  ENSMUST00000173615 Pkn2-011 142809642-142821598 nonsense_mediated_decay
  ENSMUST00000173830 Pkn2-007 142793811-142881658 protein_coding
  ENSMUST00000173913 Pkn2-006 142793709-142881915 nonsense_mediated_decay
  ENSMUST00000174099 Pkn2-008 142821309-142829258 retained_intron
  ENSMUST00000174169 Pkn2-010 142810759-142812582 retained_intron
  ENSMUST00000174422 Pkn2-005 142793811-142881658 protein_coding
  ENSMUST00000174680 Pkn2-009 142811553-142829295 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043812ENSMUST00000172521ENSMUST00000172916ENSMUST00000173830ENSMUST00000173913ENSMUST00000174422
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043812 6.815±2.00 4.015±0.62 4.427±1.02 4.001±0.39 5.804±0.62 5.132±1.01 3.597±0.80 6.086±0.90 5.581±3.20 7.905±1.40 0.948±0.24 7.127±0.76 8.165±4.41 3.799±0.82
ENSMUST00000172521 3.150±0.00 2.602±0.00 N/A N/A 2.206±0.00 4.338±0.17 N/A 2.809±0.53 0.784±0.00 3.121±0.00 N/A 3.805±0.00 N/A 3.652±0.59
ENSMUST00000172916 N/A 37.298±12.60 N/A 3.380±0.00 24.496±1.80 18.237±2.96 N/A 10.473±0.00 1.853±0.00 17.632±8.42 N/A 28.769±6.58 62.856±8.73 13.221±0.00
ENSMUST00000173830 N/A N/A N/A 4.707±0.00 N/A N/A N/A N/A N/A N/A N/A 12.742±0.00 13.698±0.00 8.062±0.00
ENSMUST00000173913 N/A N/A N/A N/A N/A N/A 1.080±0.00 N/A N/A N/A N/A N/A 13.587±2.35 3.775±0.77
ENSMUST00000174422 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 13.609±0.00 24.285±4.07 14.546±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000F6 CIL_0000F6_0002 CGP 3:142765226-142882004

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 ISS protein serine/threonine kinase activity
GO:0004697 IEA protein kinase C activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005813 IEA centrosome
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006468 ISS protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007049 IEA cell cycle
GO:0007155 IEA cell adhesion
GO:0007165 IEA signal transduction
GO:0010631 ISS epithelial cell migration
GO:0016020 IEA membrane
GO:0030027 ISS lamellipodium
GO:0030496 ISS midbody
GO:0032154 ISS cleavage furrow
GO:0032467 ISS positive regulation of cytokinesis
GO:0042826 ISS histone deacetylase binding
GO:0043296 IDA apical junction complex
GO:0043297 IDA apical junction assembly
GO:0044822 IEA poly(A) RNA binding
GO:0045111 IEA intermediate filament cytoskeleton
GO:0045931 ISS positive regulation of mitotic cell cycle
GO:0051301 IEA cell division
GO:2000145 ISS regulation of cell motility

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006705 pkn2 protein kinase N2 protein_coding Danio_rerio
ENSDARG00000036707 PKN2 (2 of 2) protein kinase N2 protein_coding Danio_rerio
ENSG00000065243 PKN2 protein kinase N2 protein_coding Homo_sapiens

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