C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAS p21 protein activator 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004952 Rasa4 10090 + 5:136083916-136111860 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000042135 Rasa4-001 136083916-136111860 protein_coding
  ENSMUST00000100570 Rasa4-006 136084032-136111860 protein_coding
  ENSMUST00000122887 Rasa4-011 136103894-136106033 protein_coding
  ENSMUST00000125048 Rasa4-003 136083998-136109961 retained_intron
  ENSMUST00000125247 Rasa4-009 136085070-136091264 processed_transcript
  ENSMUST00000130598 Rasa4-012 136110932-136111530 retained_intron
  ENSMUST00000131353 Rasa4-008 136083999-136093447 retained_intron
  ENSMUST00000134509 Rasa4-002 136083954-136111860 retained_intron
  ENSMUST00000135344 Rasa4-004 136083998-136111855 retained_intron
  ENSMUST00000140972 Rasa4-007 136084089-136107511 retained_intron
  ENSMUST00000145294 Rasa4-010 136095590-136102295 nonsense_mediated_decay
  ENSMUST00000152723 Rasa4-005 136084018-136111855 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000042135ENSMUST00000100570ENSMUST00000125048ENSMUST00000134509ENSMUST00000135344ENSMUST00000140972ENSMUST00000145294ENSMUST00000152723
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000042135 5.266±2.01 8.354±1.28 2.632±0.43 1.885±1.29 8.987±1.94 8.816±1.83 1.103±0.32 2.035±0.34 0.699±0.42 3.414±0.59 7.387±1.54 4.756±1.76 0.538±0.27 0.570±0.24
ENSMUST00000100570 N/A N/A N/A N/A 5.900±0.00 N/A N/A N/A N/A N/A N/A 3.668±1.29 0.549±0.00 0.138±0.02
ENSMUST00000125048 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.771±0.54 1.151±0.27 N/A N/A
ENSMUST00000134509 2.344±1.11 3.255±0.38 0.870±0.15 0.628±0.00 3.139±0.22 4.323±1.16 0.482±0.15 0.759±0.08 0.269±0.14 0.967±0.29 N/A 1.813±0.43 0.248±0.19 0.200±0.00
ENSMUST00000135344 2.248±0.41 4.379±0.00 1.320±0.04 1.409±0.85 3.491±0.62 6.196±1.70 0.433±0.00 0.678±0.17 0.547±0.25 0.882±0.00 5.110±0.50 4.366±1.50 0.707±0.70 N/A
ENSMUST00000140972 N/A N/A N/A 0.458±0.00 N/A N/A 0.519±0.08 N/A 0.049±0.00 0.816±0.05 3.970±0.37 1.371±0.00 0.405±0.18 N/A
ENSMUST00000145294 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.823±0.00
ENSMUST00000152723 N/A N/A N/A N/A 2.795±0.00 N/A N/A 0.568±0.00 0.397±0.00 N/A N/A 3.128±0.56 0.383±0.00 0.323±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001GU CIL_0001GU_0002 CGP 5:136054492-136111860

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005099 IBA Ras GTPase activator activity
GO:0005737 IBA cytoplasm
GO:0031235 IBA intrinsic component of the cytoplasmic side of the plasma membrane
GO:0032320 IBA positive regulation of Ras GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0046580 IBA negative regulation of Ras protein signal transduction
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029372 rasa4 RAS p21 protein activator 4 protein_coding Danio_rerio
ENSG00000105808 RASA4 RAS p21 protein activator 4 protein_coding Homo_sapiens
ENSG00000170667 RASA4B RAS p21 protein activator 4B protein_coding Homo_sapiens

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