Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSMUSG00000005225	Plekha8	10090	+	6:54595111-54645839	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENSMUST00000101385		Plekha8-002	54603147-54641033	protein_coding
	ENSMUST00000119706		Plekha8-001	54595111-54645839	protein_coding

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENSMUST00000101385	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	0.651±0.13	N/A	3.605±0.67	5.923±1.18
ENSMUST00000119706	3.496±1.67	3.501±0.47	2.286±0.33	4.193±2.21	2.197±0.55	12.691±0.73	1.510±0.15	3.923±0.52	2.644±1.16	3.301±0.20	0.465±0.10	7.977±2.31	2.631±0.60	6.070±2.57

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_0003ZB	CIL_0003ZB_0002	CGP	6:54505890-54597344
CIL_0003ZA	CIL_0003ZA_0002	CGP	6:54577604-54645839

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0005802	ISS	trans-Golgi network
GO:0006869	ISS	lipid transport
GO:0016020	IEA	membrane
GO:0017089	ISS	glycolipid transporter activity
GO:0035621	ISS	ER to Golgi ceramide transport
GO:0046836	IEA	glycolipid transport
GO:0051861	ISS	glycolipid binding
GO:0070273	ISS	phosphatidylinositol-4-phosphate binding
GO:0097001	ISS	ceramide binding

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000040698	plekha8	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8	protein_coding	Danio_rerio
ENSG00000106086	PLEKHA8	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8	protein_coding	Homo_sapiens

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