C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heme oxygenase (decycling) 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005413 Hmox1 10090 + 8:75093591-75100596 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005548 Hmox1-001 75093591-75100596 protein_coding
  ENSMUST00000159631 Hmox1-002 75093850-75097204 protein_coding
  ENSMUST00000160341 Hmox1-003 75093641-75096451 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005548ENSMUST00000159631
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005548 10.032±2.21 23.151±7.34 7.174±0.59 1.788±0.97 10.570±4.19 2.685±1.22 2.292±1.16 6.279±1.27 37.909±34.88 12.691±0.33 3.419±0.59 17.375±4.93 112.369±60.99 2.843±0.97
ENSMUST00000159631 N/A N/A N/A 0.467±0.00 N/A 2.097±0.12 N/A N/A N/A N/A N/A 12.636±2.18 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002NF CIL_0002NF_0002 CGP 8:75033686-75100596
CIL_0006NI CIL_0006NI_0003 CGP 8:75093591-75128439

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001666 IEA response to hypoxia
GO:0002246 IEA wound healing involved in inflammatory response
GO:0004392 IEA heme oxygenase (decyclizing) activity
GO:0004630 IEA phospholipase D activity
GO:0004871 IEA signal transducer activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005730 IEA nucleolus
GO:0005783 IEA endoplasmic reticulum
GO:0005829 IEA cytosol
GO:0005901 IEA caveola
GO:0006788 IEA heme oxidation
GO:0006979 IEA response to oxidative stress
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008217 IEA regulation of blood pressure
GO:0008219 IEA cell death
GO:0008285 IEA negative regulation of cell proliferation
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010656 IEA negative regulation of muscle cell apoptotic process
GO:0016491 IEA oxidoreductase activity
GO:0019899 IEA enzyme binding
GO:0020037 IEA heme binding
GO:0031670 IEA cellular response to nutrient
GO:0032764 IEA negative regulation of mast cell cytokine production
GO:0034101 IEA erythrocyte homeostasis
GO:0034395 IDA regulation of transcription from RNA polymerase II promoter in response to iron
GO:0035094 IEA response to nicotine
GO:0035556 IEA intracellular signal transduction
GO:0042167 IEA heme catabolic process
GO:0042168 IDA heme metabolic process
GO:0042542 IEA response to hydrogen peroxide
GO:0042803 IEA protein homodimerization activity
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043305 IEA negative regulation of mast cell degranulation
GO:0043392 IEA negative regulation of DNA binding
GO:0043433 IEA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0043619 IEA regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0043627 IEA response to estrogen
GO:0045766 IEA positive regulation of angiogenesis
GO:0046872 IEA metal ion binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0048662 IEA negative regulation of smooth muscle cell proliferation
GO:0051090 IEA regulation of sequence-specific DNA binding transcription factor activity
GO:0051260 IEA protein homooligomerization
GO:0055072 IEA iron ion homeostasis
GO:0071243 IDA cellular response to arsenic-containing substance
GO:0071276 IDA cellular response to cadmium ion
GO:0071456 IEA cellular response to hypoxia
GO:1902042 IEA negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027529 hmox1a heme oxygenase (decycling) 1a protein_coding Danio_rerio
ENSG00000100292 HMOX1 heme oxygenase (decycling) 1 protein_coding Homo_sapiens

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