C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: orthodenticle homolog 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005917 Otx1 10090 - 11:21994764-22002897 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006071 Otx1-001 21994764-22001615 protein_coding
  ENSMUST00000147486 Otx1-003 21996858-22002897 protein_coding
  ENSMUST00000172395 Otx1-002 21994769-22001710 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000006071ENSMUST00000147486ENSMUST00000172395
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000006071 0.021±0.00 0.005±0.00 4.825±3.32 0.013±0.01 0.013±0.00 0.121±0.10 0.009±0.00 0.030±0.04 0.359±0.14 0.115±0.05 0.115±0.10 0.061±0.01
ENSMUST00000147486 N/A N/A N/A N/A 0.088±0.00 N/A N/A N/A N/A 0.152±0.00 0.071±0.02 0.155±0.00
ENSMUST00000172395 N/A 0.005±0.00 0.450±0.25 N/A 0.018±0.00 0.024±0.00 N/A 0.005±0.00 0.029±0.00 N/A 0.022±0.01 0.020±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007MW CIL_0007MW_0003 UCNEbase 11:21694041-22206768
CIL_00095K CIL_00095K_0002 VISTA 11:21702480-22303824
CIL_00090Q CIL_00090Q_0002 VISTA 11:21710037-22311279
CIL_00084N CIL_00084N_0002 VISTA 11:21768163-22368901
CIL_000976 CIL_000976_0002 VISTA 11:21778416-22379452

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0005515 IPI protein binding
GO:0005634 IC nucleus
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0009952 IGI anterior/posterior pattern specification
GO:0022037 IGI metencephalon development
GO:0030900 IGI forebrain development
GO:0030901 IGI midbrain development
GO:0042472 IGI inner ear morphogenesis
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048852 IGI diencephalon morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030703 otx1a orthodenticle homolog 1a protein_coding Danio_rerio
ENSDARG00000094992 otx1b orthodenticle homolog 1b protein_coding Danio_rerio
ENSG00000115507 OTX1 orthodenticle homeobox 1 protein_coding Homo_sapiens

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