C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000006014 Prg4 10090 - 1:150449412-150466165 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006171 Prg4-201 150449412-150465598 protein_coding
  ENSMUST00000111901 Prg4-202 150449412-150465598 protein_coding
  ENSMUST00000111902 Prg4-203 150449412-150465598 protein_coding
  ENSMUST00000159035 Prg4-004 150458192-150466165 protein_coding
  ENSMUST00000161320 Prg4-005 150455997-150466165 protein_coding
  ENSMUST00000161611 Prg4-002 150449869-150466165 protein_coding
  ENSMUST00000162367 Prg4-001 150449816-150466165 protein_coding
  ENSMUST00000164600 Prg4-204 150449412-150465598 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LiverENSMUST00000161611ENSMUST00000162367
Transcript ID Liver
ENSMUST00000161611 1.987±0.02
ENSMUST00000162367 11.611±2.48

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005044 IEA scavenger receptor activity
GO:0005615 IDA extracellular space
GO:0005737 IEA cytoplasm
GO:0006898 IEA receptor-mediated endocytosis
GO:0006955 IEA immune response
GO:0018149 IEA peptide cross-linking
GO:0030247 IEA polysaccharide binding
GO:0042127 IMP regulation of cell proliferation
GO:0045409 IMP negative regulation of interleukin-6 biosynthetic process
GO:0071425 IMP hematopoietic stem cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010482 prg4a proteoglycan 4a protein_coding Danio_rerio
ENSDARG00000028163 prg4b proteoglycan 4b protein_coding Danio_rerio
ENSG00000116690 PRG4 proteoglycan 4 protein_coding Homo_sapiens

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