C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: EPS8-like 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000006154 Eps8l1 10090 + 7:4460674-4479404 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000086372 Eps8l1-004 4464742-4479242 protein_coding
  ENSMUST00000163137 Eps8l1-003 4464861-4479240 nonsense_mediated_decay
  ENSMUST00000163804 Eps8l1-007 4460674-4469970 nonsense_mediated_decay
  ENSMUST00000163893 Eps8l1-001 4464849-4479403 protein_coding
  ENSMUST00000164987 Eps8l1-014 4477666-4479244 nonsense_mediated_decay
  ENSMUST00000167068 Eps8l1-015 4472475-4474584 processed_transcript
  ENSMUST00000167298 Eps8l1-006 4460702-4469227 protein_coding
  ENSMUST00000167599 Eps8l1-010 4464742-4470179 retained_intron
  ENSMUST00000167810 Eps8l1-008 4464493-4470834 protein_coding
  ENSMUST00000168924 Eps8l1-013 4477428-4477970 processed_transcript
  ENSMUST00000169820 Eps8l1-009 4464769-4470042 protein_coding
  ENSMUST00000170423 Eps8l1-005 4464735-4469369 retained_intron
  ENSMUST00000170635 Eps8l1-011 4464869-4469919 protein_coding
  ENSMUST00000171445 Eps8l1-002 4460715-4479404 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000086372ENSMUST00000163137ENSMUST00000163804ENSMUST00000163893ENSMUST00000164987ENSMUST00000167298ENSMUST00000167810ENSMUST00000170635ENSMUST00000171445
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000086372 1.060±0.00 N/A 1.662±0.32 N/A 2.573±0.34 0.714±0.06 0.080±0.00 1.122±0.02 0.214±0.13 6.804±0.96 0.422±0.19 1.730±1.00 1.761±1.49 0.064±0.00
ENSMUST00000163137 0.283±0.18 0.303±0.04 0.865±0.01 0.455±0.00 N/A 0.411±0.08 0.052±0.02 N/A 0.098±0.03 1.759±0.12 N/A 0.603±0.28 0.303±0.15 0.061±0.03
ENSMUST00000163804 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.395±0.00 N/A N/A N/A
ENSMUST00000163893 0.585±0.00 0.267±0.00 1.133±0.09 N/A 2.463±0.90 1.174±0.25 N/A 1.833±0.00 0.123±0.00 7.957±1.22 N/A 1.319±1.02 0.760±0.52 0.042±0.00
ENSMUST00000164987 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.642±0.00 11.100±0.00 11.701±6.98 1.435±0.00
ENSMUST00000167298 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.614±0.00 N/A N/A 0.666±0.00
ENSMUST00000167810 N/A N/A N/A N/A N/A N/A N/A N/A 0.423±0.00 N/A N/A N/A N/A 0.176±0.02
ENSMUST00000170635 N/A N/A N/A N/A N/A N/A N/A N/A 0.150±0.00 N/A N/A N/A N/A N/A
ENSMUST00000171445 1.535±0.80 0.794±0.24 2.402±0.04 1.362±0.00 1.726±0.25 0.779±0.16 0.137±0.03 2.642±0.53 0.503±0.36 N/A 0.464±0.04 1.682±1.00 1.334±0.08 0.153±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00068Q CIL_00068Q_0002 CGP 7:4424770-4479404
CIL_0004TI CIL_0004TI_0002 CGP 7:4460674-4501680

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001726 ISA ruffle
GO:0003779 IEA actin binding
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005737 IEA cytoplasm
GO:0007266 IEA Rho protein signal transduction
GO:0016601 ISA Rac protein signal transduction
GO:0030676 IEA Rac guanyl-nucleotide exchange factor activity
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0032587 IEA ruffle membrane
GO:0032855 IEA positive regulation of Rac GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0042608 IEA T cell receptor binding
GO:0043234 IEA protein complex
GO:0051015 ISA actin filament binding
GO:0070062 IEA extracellular vesicular exosome
GO:1900029 IEA positive regulation of ruffle assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003313 EPS8L1 (1 of 2) EPS8-like 1 protein_coding Danio_rerio
ENSDARG00000057984 eps8l1 eps8-like1 protein_coding Danio_rerio
ENSG00000131037 EPS8L1 EPS8-like 1 protein_coding Homo_sapiens

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