C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000006378 Gcat 10090 + 15:79030874-79043558 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006544 Gcat-201 79030874-79038348 protein_coding
  ENSMUST00000058004 Gcat-202 79041885-79043558 protein_coding
  ENSMUST00000171999 Gcat-203 79030874-79042531 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000006544ENSMUST00000171999
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006544 3.438±0.40 5.930±0.60 3.459±0.02 2.255±0.64 2.907±0.91 3.602±1.21 2.996±0.26 25.103±1.49 24.751±5.93 2.232±0.38 2.729±0.38 2.615±0.83 15.448±17.96 0.846±0.33
ENSMUST00000171999 8.860±1.95 21.337±4.56 2.849±1.32 2.055±1.25 9.594±4.45 11.029±1.72 3.830±0.22 42.708±7.88 54.477±31.09 6.989±0.49 1.072±0.36 7.234±1.77 24.754±23.28 1.401±0.31

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099H CIL_00099H_0002 VISTA 15:78863840-79464236
CIL_0008KJ CIL_0008KJ_0002 VISTA 15:78865517-79466323
CIL_0008BX CIL_0008BX_0002 VISTA 15:78873761-79474273
CIL_0008KA CIL_0008KA_0002 VISTA 15:78875821-79476550
CIL_00082J CIL_00082J_0002 VISTA 15:78908803-79509777
CIL_0008C1 CIL_0008C1_0002 VISTA 15:78918952-79520098
CIL_00082K CIL_00082K_0002 VISTA 15:78923635-79524085
CIL_0008MM CIL_0008MM_0002 VISTA 15:79023554-79624112
CIL_000409 CIL_000409_0002 CGP 15:79028212-79043558

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004966 ISS galanin receptor activity
GO:0005634 IEA nucleus
GO:0005739 IEA mitochondrion
GO:0005886 IEA plasma membrane
GO:0007194 IEA negative regulation of adenylate cyclase activity
GO:0007218 IEA neuropeptide signaling pathway
GO:0008890 IEA glycine C-acetyltransferase activity
GO:0009058 IEA biosynthetic process
GO:0016021 IEA integral component of membrane
GO:0017046 ISS peptide hormone binding
GO:0019518 IEA L-threonine catabolic process to glycine
GO:0030170 IEA pyridoxal phosphate binding
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005643 gcat glycine C-acetyltransferase protein_coding Danio_rerio
ENSG00000100116 GCAT glycine C-acetyltransferase protein_coding Homo_sapiens

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