C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hemochromatosis
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000006611 Hfe 10090 - 13:23702034-23710854 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006787 Hfe-004 23704386-23710714 protein_coding
  ENSMUST00000091706 Hfe-001 23703840-23710854 protein_coding
  ENSMUST00000091707 Hfe-003 23704386-23710714 protein_coding
  ENSMUST00000151243 Hfe-002 23702034-23705688 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000006787ENSMUST00000091706ENSMUST00000091707ENSMUST00000151243
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006787 N/A N/A N/A N/A N/A 2.721±0.00 N/A N/A N/A N/A N/A N/A 0.621±0.00 N/A
ENSMUST00000091706 47.979±26.41 20.750±1.04 6.824±0.05 0.794±0.16 18.920±1.82 6.001±1.56 7.981±0.35 9.701±0.97 17.187±11.11 16.235±2.65 7.926±1.01 11.565±2.52 1.860±1.22 2.872±0.99
ENSMUST00000091707 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.656±0.00 N/A N/A N/A
ENSMUST00000151243 7.388±3.67 3.940±1.03 0.792±0.00 0.100±0.03 4.526±1.42 N/A N/A 2.266±0.04 1.139±0.36 3.333±0.40 0.990±0.00 1.765±0.66 0.171±0.10 0.930±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001916 IEA positive regulation of T cell mediated cytotoxicity
GO:0002474 IEA antigen processing and presentation of peptide antigen via MHC class I
GO:0005102 IEA receptor binding
GO:0005769 IEA early endosome
GO:0006955 IEA immune response
GO:0007565 IEA female pregnancy
GO:0010106 IEA cellular response to iron ion starvation
GO:0016021 IEA integral component of membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0042446 IMP hormone biosynthetic process
GO:0042605 IEA peptide antigen binding
GO:0042612 IEA MHC class I protein complex
GO:0045177 IEA apical part of cell
GO:0045178 IEA basal part of cell
GO:0048471 IEA perinuclear region of cytoplasm
GO:0055037 IEA recycling endosome
GO:0055072 IMP iron ion homeostasis
GO:0060586 IMP multicellular organismal iron ion homeostasis
GO:0097459 IMP iron ion import into cell

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000010704 HFE hemochromatosis protein_coding Homo_sapiens

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