Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	neuraminidase 1
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSMUSG00000007038	Neu1	10090	+	17:34931253-34935953	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENSMUST00000007253		Neu1-001	34931253-34935921	protein_coding
	ENSMUST00000173269		Neu1-002	34931314-34935953	retained_intron
	ENSMUST00000174715		Neu1-003	34931863-34932765	retained_intron

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENSMUST00000007253	12.569±4.96	26.807±2.61	9.935±2.46	7.777±3.97	14.996±5.79	68.969±28.82	3.245±1.32	94.743±32.65	12.782±6.62	14.260±1.30	5.616±1.19	13.614±4.66	32.231±7.41	2.194±1.14
ENSMUST00000173269	3.974±0.34	3.422±0.11	3.232±0.68	2.985±0.85	4.250±0.77	12.352±2.30	0.943±0.13	N/A	2.497±0.46	3.477±0.15	0.704±0.20	4.191±1.10	4.384±1.68	0.222±0.00

Conserved Regions
Gene is not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0004308	IDA	exo-alpha-sialidase activity
GO:0005515	IPI	protein binding
GO:0005764	IDA	lysosome
GO:0005886	IEA	plasma membrane
GO:0009313	ISS	oligosaccharide catabolic process
GO:0016042	IEA	lipid catabolic process
GO:0030054	IEA	cell junction
GO:0031410	IEA	cytoplasmic vesicle
GO:0043231	IEA	intracellular membrane-bounded organelle
GO:0052794	IEA	exo-alpha-(2->3)-sialidase activity
GO:0052795	IEA	exo-alpha-(2->6)-sialidase activity
GO:0052796	IEA	exo-alpha-(2->8)-sialidase activity
GO:0070062	IEA	extracellular vesicular exosome

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000008832	neu1	neuraminidase 1	protein_coding	Danio_rerio
ENSG00000204386	NEU1	sialidase 1 (lysosomal sialidase)	protein_coding	Homo_sapiens

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