C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cathepsin D
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000007891 Ctsd 10090 - 7:142371148-142388038 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000066401 Ctsd-003 142375929-142387819 nonsense_mediated_decay
  ENSMUST00000133843 Ctsd-004 142371148-142382667 protein_coding
  ENSMUST00000151120 Ctsd-001 142375910-142388038 protein_coding
  ENSMUST00000153679 Ctsd-002 142383194-142387819 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000066401ENSMUST00000133843ENSMUST00000151120
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000066401 557.683±135.51 172.199±59.91 N/A 99.433±0.00 451.658±81.86 35.244±6.09 97.053±11.70 53.197±4.56 76.701±16.87 70.816±8.33 N/A 154.679±42.90 210.918±38.92 5.391±0.00
ENSMUST00000133843 N/A N/A N/A 184.262±0.00 N/A N/A N/A N/A N/A N/A N/A 411.498±0.00 524.411±59.24 23.427±0.00
ENSMUST00000151120 885.532±258.53 370.678±64.37 412.845±53.07 68.316±1.87 339.733±69.80 147.731±14.48 348.229±17.59 332.921±51.74 159.643±39.79 349.537±11.52 239.173±5.02 299.579±56.23 293.341±28.93 29.104±13.79

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MR CIL_0008MR_0002 VISTA 7:142247512-142849546
CIL_0007RG CIL_0007RG_0002 VISTA 7:142251566-142854813
CIL_00097V CIL_00097V_0002 VISTA 7:142268912-142873912
CIL_00048D CIL_00048D_0002 CGP 7:142325837-142388038
CIL_00048K CIL_00048K_0002 CGP 7:142371148-142440396

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000045 IMP autophagic vacuole assembly
GO:0004190 IDA aspartic-type endopeptidase activity
GO:0005739 IDA mitochondrion
GO:0005764 IDA lysosome
GO:0006508 IC proteolysis
GO:0008233 IDA peptidase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057698 ctsd cathepsin D protein_coding Danio_rerio
ENSG00000117984 CTSD cathepsin D protein_coding Homo_sapiens
ENSG00000250644 RP11-295K3.1 Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000415840} protein_coding Homo_sapiens

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