C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: homeodomain interacting protein kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000008730 Hipk1 10090 - 3:103739815-103791563 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029438 Hipk1-003 103743660-103791179 protein_coding
  ENSMUST00000106845 Hipk1-005 103743562-103791075 protein_coding
  ENSMUST00000118317 Hipk1-001 103739815-103791563 protein_coding
  ENSMUST00000121324 Hipk1-004 103743884-103791179 protein_coding
  ENSMUST00000126351 Hipk1-007 103749363-103751014 retained_intron
  ENSMUST00000135634 Hipk1-006 103754157-103791275 retained_intron
  ENSMUST00000137078 Hipk1-002 103745156-103791561 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000029438ENSMUST00000118317ENSMUST00000121324ENSMUST00000135634ENSMUST00000137078
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000029438 10.135±1.13 14.722±4.22 N/A N/A 18.365±5.90 20.590±5.30 6.190±1.35 10.604±3.92 7.349±1.12 17.808±0.00 26.211±11.04 3.496±0.20 N/A
ENSMUST00000118317 7.588±2.77 17.897±3.02 5.743±2.76 2.835±0.13 16.047±2.29 18.334±0.83 3.983±1.59 4.287±0.90 9.235±7.89 34.073±7.65 19.881±3.65 1.644±0.89 10.804±1.56
ENSMUST00000121324 N/A 17.958±3.74 N/A N/A N/A 12.078±0.00 N/A N/A N/A 9.095±0.00 10.859±2.03 N/A N/A
ENSMUST00000135634 N/A N/A N/A 7.775±0.00 N/A N/A N/A N/A N/A N/A N/A 3.739±0.26 N/A
ENSMUST00000137078 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 47.543±10.93

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0003714 ISS transcription corepressor activity
GO:0004672 ISS protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006468 ISS protein phosphorylation
GO:0007224 IGI smoothened signaling pathway
GO:0008284 IGI positive regulation of cell proliferation
GO:0009952 IGI anterior/posterior pattern specification
GO:0010803 IEA regulation of tumor necrosis factor-mediated signaling pathway
GO:0010842 IMP retina layer formation
GO:0016605 IDA PML body
GO:0016607 IDA nuclear speck
GO:0030182 IMP neuron differentiation
GO:0042771 IGI intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043388 ISS positive regulation of DNA binding
GO:0048596 IMP embryonic camera-type eye morphogenesis
GO:0060059 IMP embryonic retina morphogenesis in camera-type eye
GO:0060235 IMP lens induction in camera-type eye
GO:0061072 IMP iris morphogenesis
GO:0072577 IEA endothelial cell apoptotic process
GO:0097191 IEA extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063594 HIPK1 (1 of 2) homeodomain interacting protein kinase 1 protein_coding Danio_rerio
ENSDARG00000077095 HIPK1 (2 of 2) homeodomain interacting protein kinase 1 protein_coding Danio_rerio
ENSG00000163349 HIPK1 homeodomain interacting protein kinase 1 protein_coding Homo_sapiens

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