C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: folylpolyglutamyl synthetase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000009566 Fpgs 10090 - 2:32682609-32704137 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028148 Fpgs-001 32682609-32694185 protein_coding
  ENSMUST00000123171 Fpgs-005 32686502-32687502 processed_transcript
  ENSMUST00000127812 Fpgs-009 32687416-32704134 protein_coding
  ENSMUST00000130164 Fpgs-002 32682610-32694135 processed_transcript
  ENSMUST00000132327 Fpgs-003 32682817-32685956 processed_transcript
  ENSMUST00000142186 Fpgs-004 32683302-32685004 processed_transcript
  ENSMUST00000143743 Fpgs-010 32692713-32704031 processed_transcript
  ENSMUST00000146498 Fpgs-008 32686849-32704137 processed_transcript
  ENSMUST00000149491 Fpgs-007 32692451-32693244 processed_transcript
  ENSMUST00000156792 Fpgs-006 32687014-32687837 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonKidneyLiverOvaryPlacentaTestisENSMUST00000028148ENSMUST00000127812
Transcript ID Adipose Bladder Brain Breast Colon Kidney Liver Ovary Placenta Testis
ENSMUST00000028148 34.068±6.34 13.559±2.39 12.137±1.99 35.040±0.41 31.087±1.77 46.112±11.59 56.403±38.44 41.447±10.92 10.788±3.78 21.960±1.54
ENSMUST00000127812 N/A N/A N/A N/A N/A N/A 55.181±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008YA CIL_0008YA_0002 VISTA 2:32608279-33209524
CIL_0000H9 CIL_0000H9_0002 CGP 2:32682609-32713076

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001889 IEA liver development
GO:0004326 IEA tetrahydrofolylpolyglutamate synthase activity
GO:0005524 IEA ATP binding
GO:0005739 IDA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0006730 IEA one-carbon metabolic process
GO:0007420 IEA brain development
GO:0031100 IEA organ regeneration
GO:0046901 IEA tetrahydrofolylpolyglutamate biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044809 fpgs folylpolyglutamate synthase protein_coding Danio_rerio
ENSG00000136877 FPGS folylpolyglutamate synthase protein_coding Homo_sapiens

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