C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000013629 Cad 10090 + 5:31054780-31078479 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000013773 Cad-001 31054780-31078479 protein_coding
  ENSMUST00000031049 Cad-003 31054955-31078195 protein_coding
  ENSMUST00000114646 Cad-002 31054811-31067760 protein_coding
  ENSMUST00000126382 Cad-004 31061794-31066968 retained_intron
  ENSMUST00000137541 Cad-005 31066295-31067180 processed_transcript
  ENSMUST00000139994 Cad-007 31070469-31072705 retained_intron
  ENSMUST00000148145 Cad-006 31070356-31072194 processed_transcript
  ENSMUST00000152004 Cad-008 31072309-31073580 retained_intron
  ENSMUST00000152509 Cad-009 31075813-31076664 retained_intron
  ENSMUST00000155001 Cad-010 31074117-31076028 protein_coding
  ENSMUST00000170329 Cad-012 31054928-31078232 protein_coding
  ENSMUST00000174367 Cad-011 31054928-31078232 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000013773ENSMUST00000031049ENSMUST00000139994ENSMUST00000170329ENSMUST00000174367
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000013773 10.032±5.91 6.578±0.95 4.452±0.16 7.879±4.97 12.385±5.12 11.213±0.92 2.275±1.04 3.022±0.60 5.528±4.12 7.324±0.82 1.111±0.55 19.168±7.66 5.756±4.24 3.243±1.48
ENSMUST00000031049 N/A N/A N/A N/A N/A 2.490±0.00 N/A 0.484±0.00 N/A 1.350±0.00 N/A N/A N/A N/A
ENSMUST00000139994 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.925±0.00 N/A
ENSMUST00000170329 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.285±0.00 N/A N/A
ENSMUST00000174367 N/A N/A N/A 1.284±0.00 1.617±0.00 N/A N/A N/A N/A N/A N/A 3.098±0.00 4.480±3.76 0.875±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000EH CIL_0000EH_0002 CGP 5:31048312-31078479
CIL_0000EG CIL_0000EG_0002 CGP 5:31054780-31108237

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001889 IEA liver development
GO:0003824 IEA catalytic activity
GO:0004070 IEA aspartate carbamoyltransferase activity
GO:0004088 IEA carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0004151 ISS dihydroorotase activity
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005829 IEA cytosol
GO:0006207 ISS 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006228 IEA UTP biosynthetic process
GO:0006541 IEA glutamine metabolic process
GO:0006543 IEA glutamine catabolic process
GO:0007507 IEA heart development
GO:0007565 IEA female pregnancy
GO:0007595 IEA lactation
GO:0008152 IEA metabolic process
GO:0008270 ISS zinc ion binding
GO:0014075 IEA response to amine
GO:0016020 IEA membrane
GO:0016363 IEA nuclear matrix
GO:0016597 IEA amino acid binding
GO:0016743 IEA carboxyl- or carbamoyltransferase activity
GO:0016810 IEA hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016812 IEA hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GO:0017144 IEA drug metabolic process
GO:0019899 IEA enzyme binding
GO:0031000 IEA response to caffeine
GO:0031100 IEA organ regeneration
GO:0033574 IEA response to testosterone
GO:0035690 IEA cellular response to drug
GO:0042802 IEA identical protein binding
GO:0042995 IEA cell projection
GO:0043025 IEA neuronal cell body
GO:0043195 IEA terminal bouton
GO:0043234 IEA protein complex
GO:0044205 IEA 'de novo' UMP biosynthetic process
GO:0046872 IEA metal ion binding
GO:0051414 IEA response to cortisol
GO:0070062 IEA extracellular vesicular exosome
GO:0070409 IEA carbamoyl phosphate biosynthetic process
GO:0071364 IEA cellular response to epidermal growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041895 cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase protein_coding Danio_rerio
ENSG00000084774 CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase protein_coding Homo_sapiens

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