C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: euchromatic histone lysine N-methyltransferase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000013787 Ehmt2 10090 + 17:34898469-34914052 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000013931 Ehmt2-001 34898971-34914051 protein_coding
  ENSMUST00000078061 Ehmt2-004 34898499-34914047 protein_coding
  ENSMUST00000097342 Ehmt2-002 34898954-34914044 protein_coding
  ENSMUST00000114033 Ehmt2-003 34898469-34914051 protein_coding
  ENSMUST00000124002 Ehmt2-012 34910975-34914052 retained_intron
  ENSMUST00000124846 Ehmt2-009 34906002-34908558 protein_coding
  ENSMUST00000131915 Ehmt2-010 34906744-34908443 processed_transcript
  ENSMUST00000137071 Ehmt2-013 34907398-34914047 nonsense_mediated_decay
  ENSMUST00000138500 Ehmt2-005 34905203-34906251 retained_intron
  ENSMUST00000145201 Ehmt2-011 34908645-34911502 retained_intron
  ENSMUST00000145624 Ehmt2-008 34905910-34906625 retained_intron
  ENSMUST00000146418 Ehmt2-007 34899694-34902624 processed_transcript
  ENSMUST00000150786 Ehmt2-006 34905240-34906040 retained_intron
  ENSMUST00000172921 Ehmt2-014 34907400-34908802 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000013931ENSMUST00000078061ENSMUST00000097342ENSMUST00000114033ENSMUST00000124002ENSMUST00000124846ENSMUST00000131915ENSMUST00000137071ENSMUST00000145201
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000013931 13.351±2.60 47.230±8.00 9.323±1.82 15.583±3.15 28.666±8.80 26.693±3.19 3.064±0.12 7.577±2.44 5.311±2.49 15.636±6.33 3.105±1.51 30.946±6.77 8.069±1.00 13.972±1.80
ENSMUST00000078061 28.064±1.28 25.451±4.45 11.032±0.13 29.841±12.84 27.200±11.83 33.534±4.22 8.051±0.24 21.227±3.08 10.553±2.37 22.124±2.43 2.186±0.56 38.759±16.09 20.951±11.03 48.074±3.96
ENSMUST00000097342 N/A 19.539±3.40 N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.703±0.77 N/A 24.336±6.31
ENSMUST00000114033 20.327±3.88 14.637±0.00 17.090±1.20 42.244±14.92 14.475±2.80 16.781±1.40 5.395±0.36 12.847±4.34 5.551±1.22 12.344±1.38 5.753±1.65 27.100±6.56 22.653±11.22 N/A
ENSMUST00000124002 N/A N/A N/A N/A 15.933±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000124846 N/A 39.356±2.84 N/A N/A N/A 32.832±0.00 N/A N/A N/A N/A N/A 39.254±4.36 N/A N/A
ENSMUST00000131915 N/A N/A N/A 81.345±0.00 N/A N/A N/A N/A N/A N/A N/A 91.978±0.00 45.783±0.00 N/A
ENSMUST00000137071 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.177±0.00 N/A 31.742±2.40
ENSMUST00000145201 N/A N/A N/A 66.292±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 50.419±8.38 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005694 IEA chromosome
GO:0006275 IMP regulation of DNA replication
GO:0006306 IDA DNA methylation
GO:0006357 IMP regulation of transcription from RNA polymerase II promoter
GO:0007130 IMP synaptonemal complex assembly
GO:0007281 IMP germ cell development
GO:0007286 IMP spermatid development
GO:0008270 IEA zinc ion binding
GO:0009566 IMP fertilization
GO:0010424 IMP DNA methylation on cytosine within a CG sequence
GO:0016571 IMP histone methylation
GO:0018024 IMP histone-lysine N-methyltransferase activity
GO:0018027 ISS peptidyl-lysine dimethylation
GO:0035265 IMP organ growth
GO:0046974 IDA histone methyltransferase activity (H3-K9 specific)
GO:0046976 IDA histone methyltransferase activity (H3-K27 specific)
GO:0051567 IMP histone H3-K9 methylation
GO:0070734 IMP histone H3-K27 methylation
GO:0070742 IPI C2H2 zinc finger domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077703 ehmt2 euchromatic histone-lysine N-methyltransferase 2 protein_coding Danio_rerio
ENSG00000204371 EHMT2 euchromatic histone-lysine N-methyltransferase 2 protein_coding Homo_sapiens

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