C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lipoprotein lipase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000015568 Lpl 10090 + 8:68880491-68907448 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000015712 Lpl-001 68880491-68906934 protein_coding
  ENSMUST00000101463 Lpl-003 68880657-68889681 retained_intron
  ENSMUST00000168401 Lpl-002 68880555-68907448 nonsense_mediated_decay
  ENSMUST00000169749 Lpl-004 68890744-68895819 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000015712ENSMUST00000101463ENSMUST00000168401
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000015712 680.913±438.74 33.293±9.80 20.800±3.22 2.118±1.11 213.649±21.93 4.317±1.27 434.204±27.19 54.902±11.38 27.550±41.50 30.006±1.83 113.712±26.00 28.091±28.19 6.550±3.62 1.216±0.73
ENSMUST00000101463 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.486±0.00
ENSMUST00000168401 1599.247±1108.75 142.821±48.95 8.529±0.00 14.154±0.00 434.160±66.76 13.707±2.76 374.572±79.05 49.005±21.49 4.084±3.05 29.768±8.93 N/A 77.435±15.27 5.066±3.08 2.309±1.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003TK CIL_0003TK_0002 CGP 8:68793929-68907448
CIL_0003TS CIL_0003TS_0002 CGP 8:68880491-69089235

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004465 IDA lipoprotein lipase activity
GO:0004806 IDA triglyceride lipase activity
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005886 IEA plasma membrane
GO:0008201 IEA heparin binding
GO:0009409 IEA response to cold
GO:0009986 IDA cell surface
GO:0010744 IGI positive regulation of macrophage derived foam cell differentiation
GO:0010886 IEA positive regulation of cholesterol storage
GO:0010890 IEA positive regulation of sequestering of triglyceride
GO:0016042 IEA lipid catabolic process
GO:0017129 IEA triglyceride binding
GO:0019432 IEA triglyceride biosynthetic process
GO:0019433 IDA triglyceride catabolic process
GO:0031012 IEA extracellular matrix
GO:0031225 IEA anchored component of membrane
GO:0034185 IEA apolipoprotein binding
GO:0034361 IEA very-low-density lipoprotein particle
GO:0042493 IEA response to drug
GO:0042627 IEA chylomicron
GO:0070062 IEA extracellular vesicular exosome
GO:0070328 IEA triglyceride homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087697 lpl lipoprotein lipase protein_coding Danio_rerio
ENSDARG00000091659 LPL (2 of 2) lipoprotein lipase protein_coding Danio_rerio
ENSG00000175445 LPL lipoprotein lipase protein_coding Homo_sapiens

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