Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSMUSG00000016526	Dyrk3	10090	-	1:131127455-131138340	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENSMUST00000016670		Dyrk3-001	131127455-131138340	protein_coding
	ENSMUST00000189756		Dyrk3-003	131129875-131138245	protein_coding

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENSMUST00000016670	0.991±0.94	2.550±0.61	0.210±0.04	2.037±0.44	0.722±0.23	0.438±0.07	0.080±0.02	0.675±0.18	1.493±1.20	1.615±0.46	0.040±0.00	4.121±1.34	0.958±0.64	43.220±15.27
ENSMUST00000189756	0.134±0.00	N/A	N/A	2.690±0.00	N/A	0.205±0.00	0.129±0.07	N/A	N/A	N/A	N/A	3.677±0.76	4.014±0.00	35.718±0.00

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_0004IS	CIL_0004IS_0002	CGP	1:131053700-131138340

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0000287	IDA	magnesium ion binding
GO:0004672	IDA	protein kinase activity
GO:0004674	IEA	protein serine/threonine kinase activity
GO:0004712	IEA	protein serine/threonine/tyrosine kinase activity
GO:0004713	ISA	protein tyrosine kinase activity
GO:0005515	IPI	protein binding
GO:0005524	IDA	ATP binding
GO:0005634	ISS	nucleus
GO:0006468	IDA	protein phosphorylation
GO:0018108	ISA	peptidyl-tyrosine phosphorylation
GO:0030218	IDA	erythrocyte differentiation

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000070600	DYRK3	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3	protein_coding	Danio_rerio
ENSG00000143479	DYRK3	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3	protein_coding	Homo_sapiens

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