C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000016529 Il10 10090 + 1:131019845-131024974 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000016673 Il10-001 131019845-131024974 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaENSMUST00000016673
Transcript ID Adipose Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000016673 0.075±0.05 0.132±0.01 0.006±0.00 0.453±0.06 0.142±0.08 0.037±0.00 0.052±0.03 0.089±0.03 0.034±0.01 0.163±0.16 0.052±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001T0 CIL_0001T0_0002 CGP 1:130932656-131024974
CIL_0001SF CIL_0001SF_0002 CGP 1:131019845-131097826

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001818 IEA negative regulation of cytokine production
GO:0002237 IEA response to molecule of bacterial origin
GO:0002740 IEA negative regulation of cytokine secretion involved in immune response
GO:0002875 IMP negative regulation of chronic inflammatory response to antigenic stimulus
GO:0002904 ISO positive regulation of B cell apoptotic process
GO:0005125 IDA cytokine activity
GO:0005141 IEA interleukin-10 receptor binding
GO:0005615 IDA extracellular space
GO:0006954 IEA inflammatory response
GO:0006955 IEA immune response
GO:0007568 IEA aging
GO:0010033 IEA response to organic substance
GO:0010468 ISO regulation of gene expression
GO:0014823 IEA response to activity
GO:0014854 IEA response to inactivity
GO:0030886 IMP negative regulation of myeloid dendritic cell activation
GO:0030889 ISO negative regulation of B cell proliferation
GO:0032496 IEA response to lipopolysaccharide
GO:0032689 IMP negative regulation of interferon-gamma production
GO:0032695 IMP negative regulation of interleukin-12 production
GO:0032715 IEA negative regulation of interleukin-6 production
GO:0032720 IMP negative regulation of tumor necrosis factor production
GO:0032800 IEA receptor biosynthetic process
GO:0032868 IEA response to insulin
GO:0034465 IEA response to carbon monoxide
GO:0042493 IEA response to drug
GO:0042536 IEA negative regulation of tumor necrosis factor biosynthetic process
GO:0042742 IDA defense response to bacterium
GO:0043066 IEA negative regulation of apoptotic process
GO:0044130 IMP negative regulation of growth of symbiont in host
GO:0045019 IEA negative regulation of nitric oxide biosynthetic process
GO:0045348 IDA positive regulation of MHC class II biosynthetic process
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050715 IEA positive regulation of cytokine secretion
GO:0050728 IMP negative regulation of inflammatory response
GO:0051045 IEA negative regulation of membrane protein ectodomain proteolysis
GO:0051091 IEA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051384 IEA response to glucocorticoid
GO:0051930 IEA regulation of sensory perception of pain
GO:0060670 IMP branching involved in labyrinthine layer morphogenesis
GO:0071222 IDA cellular response to lipopolysaccharide
GO:0071392 IEA cellular response to estradiol stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078147 il10 interleukin 10 protein_coding Danio_rerio
ENSG00000136634 IL10 interleukin 10 protein_coding Homo_sapiens

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