C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neighbor of Brca1 gene 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000017119 Nbr1 10090 + 11:101552149-101581951 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000071537 Nbr1-201 101556172-101581012 protein_coding
  ENSMUST00000103098 Nbr1-002 101552654-101581951 protein_coding
  ENSMUST00000103099 Nbr1-001 101552149-101581951 protein_coding
  ENSMUST00000107208 Nbr1-005 101552858-101581951 protein_coding
  ENSMUST00000107212 Nbr1-015 101552882-101581951 protein_coding
  ENSMUST00000107213 Nbr1-003 101552858-101581951 protein_coding
  ENSMUST00000107218 Nbr1-202 101556058-101581012 protein_coding
  ENSMUST00000123558 Nbr1-004 101552858-101581951 nonsense_mediated_decay
  ENSMUST00000127421 Nbr1-016 101552901-101559545 protein_coding
  ENSMUST00000127871 Nbr1-009 101566033-101568446 retained_intron
  ENSMUST00000136185 Nbr1-007 101555866-101559562 nonsense_mediated_decay
  ENSMUST00000141170 Nbr1-013 101577824-101580788 retained_intron
  ENSMUST00000144517 Nbr1-011 101568687-101569412 processed_transcript
  ENSMUST00000146452 Nbr1-008 101561786-101565781 retained_intron
  ENSMUST00000147239 Nbr1-014 101552234-101559546 protein_coding
  ENSMUST00000148805 Nbr1-012 101575107-101576631 retained_intron
  ENSMUST00000149019 Nbr1-006 101567119-101581951 protein_coding
  ENSMUST00000149170 Nbr1-010 101552867-101568540 processed_transcript
  ENSMUST00000172744 Nbr1-018 101572227-101575216 retained_intron
  ENSMUST00000174013 Nbr1-017 101568294-101569403 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000071537ENSMUST00000103099ENSMUST00000107208ENSMUST00000107212ENSMUST00000107213ENSMUST00000107218ENSMUST00000123558ENSMUST00000148805ENSMUST00000149019ENSMUST00000149170
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000071537 17.437±1.22 15.061±3.43 N/A N/A 16.442±0.65 13.582±4.27 9.032±3.52 24.467±3.84 17.398±4.39 12.111±2.70 N/A 20.614±4.58 N/A 33.632±0.00
ENSMUST00000103099 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 35.264±0.00
ENSMUST00000107208 N/A N/A N/A 5.153±0.58 N/A N/A N/A N/A 5.628±1.60 N/A N/A 11.071±3.77 7.978±1.57 N/A
ENSMUST00000107212 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.644±0.75 5.942±0.00 N/A
ENSMUST00000107213 8.027±0.91 N/A 18.357±0.70 17.369±2.75 4.079±0.60 5.971±1.12 6.133±1.61 12.226±1.25 9.396±2.65 8.500±2.11 5.820±0.35 11.857±5.76 20.795±4.47 18.223±2.64
ENSMUST00000107218 N/A N/A N/A 12.943±3.48 N/A N/A 6.773±1.41 N/A 5.298±1.10 N/A N/A 5.691±0.00 15.028±0.00 35.769±10.77
ENSMUST00000123558 N/A N/A 5.709±0.69 N/A N/A N/A N/A N/A N/A N/A 8.928±1.38 6.279±1.33 N/A N/A
ENSMUST00000148805 N/A 20.643±3.65 N/A N/A 22.570±2.99 31.122±6.88 N/A N/A 24.512±2.40 19.151±0.46 N/A 31.909±5.03 N/A N/A
ENSMUST00000149019 N/A N/A 7.724±0.60 10.495±0.00 N/A N/A 4.069±0.00 6.006±0.00 6.551±1.04 N/A 5.197±0.72 12.926±1.79 11.885±3.63 N/A
ENSMUST00000149170 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 798.506±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00040M CIL_00040M_0002 CGP 11:101488764-101581951
CIL_000996 CIL_000996_0002 VISTA 11:101501412-102102123
CIL_00090X CIL_00090X_0002 VISTA 11:101529827-102131014
CIL_0000KX CIL_0000KX_0003 CGP 11:101552149-101591788

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000407 IDA pre-autophagosomal structure
GO:0005515 IPI protein binding
GO:0005764 IEA lysosome
GO:0005770 IDA late endosome
GO:0005776 IDA autophagic vacuole
GO:0005829 ISS cytosol
GO:0008270 IEA zinc ion binding
GO:0016020 IEA membrane
GO:0016236 ISS macroautophagy
GO:0030500 IMP regulation of bone mineralization
GO:0031410 IEA cytoplasmic vesicle
GO:0032872 IMP regulation of stress-activated MAPK cascade
GO:0043130 ISS ubiquitin binding
GO:0045668 IMP negative regulation of osteoblast differentiation
GO:0051019 IDA mitogen-activated protein kinase binding
GO:0051259 ISS protein oligomerization
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077297 nbr1 neighbor of brca1 gene 1 protein_coding Danio_rerio
ENSDARG00000078772 NBR1 (2 of 2) neighbor of BRCA1 gene 1 protein_coding Danio_rerio
ENSG00000188554 NBR1 neighbor of BRCA1 gene 1 protein_coding Homo_sapiens

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