C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NIMA (never in mitosis gene a)-related expressed kinase 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000017405 Nek8 10090 - 11:78166106-78176675 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000017549 Nek8-001 78166106-78176675 protein_coding
  ENSMUST00000125528 Nek8-008 78166110-78167387 retained_intron
  ENSMUST00000131015 Nek8-003 78166521-78176627 retained_intron
  ENSMUST00000141444 Nek8-007 78167254-78168033 retained_intron
  ENSMUST00000142812 Nek8-004 78169991-78176614 retained_intron
  ENSMUST00000147798 Nek8-006 78168972-78169828 retained_intron
  ENSMUST00000148154 Nek8-005 78171187-78176634 protein_coding
  ENSMUST00000152611 Nek8-002 78166106-78176611 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000017549ENSMUST00000125528ENSMUST00000131015ENSMUST00000141444ENSMUST00000142812ENSMUST00000147798ENSMUST00000148154ENSMUST00000152611
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000017549 3.593±0.44 7.809±2.63 3.428±0.72 1.164±0.73 3.723±0.66 4.707±1.55 0.775±0.25 4.330±0.79 2.796±1.56 3.575±0.21 0.120±0.07 5.796±1.53 1.822±0.59 5.946±2.55
ENSMUST00000125528 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.224±0.11 5.924±0.00 N/A N/A
ENSMUST00000131015 1.441±0.46 N/A 1.114±0.02 0.585±0.10 1.784±0.65 1.657±0.11 0.694±0.31 1.357±0.36 0.555±0.20 1.661±0.24 0.134±0.07 2.247±0.56 1.139±0.57 0.533±0.00
ENSMUST00000141444 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.162±0.00
ENSMUST00000142812 0.923±0.18 1.928±0.16 0.887±0.25 0.497±0.10 0.904±0.09 1.322±0.00 0.297±0.09 N/A 0.741±0.35 1.077±0.05 0.068±0.02 1.864±0.53 0.568±0.18 N/A
ENSMUST00000147798 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.194±0.00 N/A N/A N/A
ENSMUST00000148154 N/A N/A N/A N/A 5.046±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000152611 1.005±0.22 3.816±1.40 1.286±0.35 0.939±0.00 2.090±0.40 3.984±0.88 0.393±0.11 2.375±0.99 1.116±0.76 1.408±0.12 0.318±0.15 4.624±0.69 N/A 2.764±0.07

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006468 IEA protein phosphorylation
GO:0009887 IEA organ morphogenesis
GO:0035330 IEA regulation of hippo signaling
GO:0046872 IEA metal ion binding
GO:0072372 IDA primary cilium
GO:0097543 IDA ciliary inversin compartment
GO:0097546 IDA ciliary base

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045626 nek8 NIMA (never in mitosis gene a)-related kinase 8 protein_coding Danio_rerio
ENSG00000160602 NEK8 NIMA-related kinase 8 protein_coding Homo_sapiens

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