C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 2, regulatory subunit B', gamma
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000017843 Ppp2r5c 10090 + 12:110485739-110583061 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000084985 Ppp2r5c-201 110485739-110583061 protein_coding
  ENSMUST00000109832 Ppp2r5c-202 110485739-110583061 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000084985ENSMUST00000109832
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000084985 6.348±0.21 3.281±0.83 8.195±1.42 N/A 4.675±1.09 2.767±1.12 6.404±0.40 3.490±0.92 1.631±0.69 7.742±1.46 5.391±1.45 4.986±2.05 2.586±0.75 22.522±0.65
ENSMUST00000109832 9.702±3.02 5.355±1.90 12.249±1.78 12.737±1.23 5.832±2.68 6.066±1.04 11.391±2.12 4.745±1.59 5.002±2.43 7.232±2.67 6.235±0.54 5.339±2.74 5.387±2.30 55.267±10.98

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004A7 CIL_0004A7_0002 CGP 12:110279068-110583061
CIL_0004A6 CIL_0004A6_0002 CGP 12:110485739-110666945

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000159 ISS protein phosphatase type 2A complex
GO:0000775 ISS chromosome, centromeric region
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0006977 IEA DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0008285 IEA negative regulation of cell proliferation
GO:0008601 IEA protein phosphatase type 2A regulator activity
GO:0042771 IEA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043161 ISO proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0050790 IEA regulation of catalytic activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031200 ppp2r5cb protein phosphatase 2, regulatory subunit B', gamma b protein_coding Danio_rerio
ENSDARG00000059083 PPP2R5C (2 of 2) protein phosphatase 2, regulatory subunit B', gamma protein_coding Danio_rerio
ENSG00000078304 PPP2R5C protein phosphatase 2, regulatory subunit B', gamma protein_coding Homo_sapiens

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