C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin carboxyl-terminal esterase L5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018189 Uchl5 10090 + 1:143777272-143807466 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018333 Uchl5-002 143777281-143807466 protein_coding
  ENSMUST00000185493 Uchl5-005 143777321-143799990 protein_coding
  ENSMUST00000185539 Uchl5-008 143794717-143806941 nonsense_mediated_decay
  ENSMUST00000185742 Uchl5-003 143777276-143784242 retained_intron
  ENSMUST00000189433 Uchl5-004 143777305-143786329 retained_intron
  ENSMUST00000189936 Uchl5-001 143777272-143807305 protein_coding
  ENSMUST00000190258 Uchl5-006 143783625-143794778 retained_intron
  ENSMUST00000191512 Uchl5-007 143794675-143797086 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018333ENSMUST00000185493ENSMUST00000185539ENSMUST00000185742ENSMUST00000189433ENSMUST00000189936ENSMUST00000190258ENSMUST00000191512
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018333 1.222±0.00 0.545±0.00 N/A 2.378±1.30 0.653±0.15 0.372±0.00 0.497±0.31 0.756±0.37 1.254±0.81 N/A 2.308±1.03 1.771±1.14 4.066±2.87 3.952±2.21
ENSMUST00000185493 N/A N/A N/A 36.652±0.00 N/A N/A N/A N/A N/A N/A N/A 13.091±11.94 45.490±34.16 58.018±0.00
ENSMUST00000185539 N/A 0.824±0.00 N/A N/A 1.011±0.14 N/A N/A N/A 1.550±0.65 N/A N/A 2.932±0.95 2.911±1.23 N/A
ENSMUST00000185742 N/A 3.412±1.23 N/A N/A 1.534±0.04 1.590±0.72 N/A N/A 2.692±0.24 N/A N/A 2.303±1.15 N/A N/A
ENSMUST00000189433 N/A 1.132±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000189936 0.854±0.21 0.543±0.00 4.755±0.75 3.914±0.40 0.768±0.26 0.904±0.46 1.056±0.43 0.988±0.44 9.075±6.53 0.693±0.00 4.798±0.64 1.594±1.17 6.397±3.97 2.141±0.64
ENSMUST00000190258 N/A N/A N/A N/A 0.591±0.00 0.432±0.00 N/A N/A N/A N/A N/A 0.870±0.53 N/A N/A
ENSMUST00000191512 N/A 2.014±0.00 N/A N/A N/A 1.477±0.00 N/A N/A 2.347±0.00 N/A N/A 1.245±0.37 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000502 IEA proteasome complex
GO:0004221 TAS ubiquitin thiolesterase activity
GO:0004843 ISS ubiquitin-specific protease activity
GO:0004866 IEA endopeptidase inhibitor activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005829 ISS cytosol
GO:0006281 IEA DNA repair
GO:0006310 IEA DNA recombination
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0008242 IEA omega peptidase activity
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0016579 ISS protein deubiquitination
GO:0021670 IMP lateral ventricle development
GO:0030901 IMP midbrain development
GO:0031011 ISS Ino80 complex
GO:0044822 IEA poly(A) RNA binding
GO:0048853 IMP forebrain morphogenesis
GO:0061136 IEA regulation of proteasomal protein catabolic process
GO:0070628 IEA proteasome binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042635 uchl5 ubiquitin carboxyl-terminal hydrolase L5 protein_coding Danio_rerio
ENSG00000116750 UCHL5 ubiquitin carboxyl-terminal hydrolase L5 protein_coding Homo_sapiens

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